The subcellular distribution of the first three enzymes in the ommochrome eye pigment pathway were studied by means of differential centrifugation. Tryptophan pyrrolase and kynurenine formamidasc are found in the soluble fraction of thc homogcnate. A relatively small amount of tryptophan pyrrolase, 10 to 15% of thc total, is sedimentable. The head region of
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