Background: There have been several studies conducted on the relationship between bipolar mood disorder and attention deficit hyperactivity disorder (ADHD) during the recent years, and in most of them the rate of this association had been estimated as 22-90% and had been reported as noticeable. The goal of this study is to determine the prevalence of ADHD in patients with Bipolar mood disorder type I (BID).Materials and Methods: In this Cross-sectional study, 152 patients with BID that were referred to psychiatric clinic of Tehran psychiatric Institute for a better observation and treatment were included. Two questionnaires, Wender’s for childhood ADHD and Conner’s’ for adulthood ADHD were filled by the patients.Results: 102 patients (67%) were males and 50 were females. The average age of patients at the time of our study (with the minimum of 17 and maximum of 76) was 33.5±10.9. The prevalence of ADHD in our patients was 11.8%. 46 people (30.9%) had a history of childhood ADHD. 21 persons had adult ADHD from whom only 3 ones mentioned a history of childhood ADHD (which means 18 people of our adulthood ADHD had no history of childhood ADHD).Conclusion: Since some treatments lead to improvement of ADHD and worsening of BID, investigations on their correlations and their alternative treatments seemed to be necessary. This study showed a significant correlation between ADHD and BID, which was similar to the results of other studies in this field.

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Childhood disintegrative disorder (CDD) is a rare autistic-like clinical condition with unknown etiology, in that previously acquired age-appropriate language, social and adaptive abilities deteriorate significantly in 2-10-year-old healthy children, although physical and neurological evaluations display no observable abnormality. Our case is a 22-year-old female born of a consanguineous marriage, with the appearance of CDD symptoms in her fifth year of age following normal mental and physical development during her initial four years of life. Without any precipitating factor, she gradually lost her language abilities, social relational skills, affectionate behavior, adaptive capacities, peer play and meaningful interest in her surrounding, friends and family members over a period of 4 years, reaching a plateau in her ninth year of age. The unique special clinical symptom in this case is a seasonal total mutism, which after the beginning of her CDD symptoms is revealing every year covering the spring. As no additional physical or psychological change accompanies her total seasonal speech loss, it cannot be attributed to any mental condition known as having a seasonal pattern. Because in the literature CDD is presented mostly as case reports with lacking of advanced research data, describing any new case is recommended to improve the knowledge about this rare condition, especially if it displays some new unusual signs, not reported till now.

Background: Psychiatric disorders are common in HIV-infected patients and for sure have direct impact on both prevention and management of diseases in these patients. In this research, the prevalence of major psychiatric disorders including mood, anxiety, and psychotic disorders in HIV-infected patients of Rafsanjan and Kerman health care centers were determined.Materials and Methods: Eighty three HIV-infected patients were interviewed by a psychiatrist in above-mentioned health centers and their information was registered through a standard CIDI questionnaire (version 2.1) and was statistically analyzed.Results: In this study, Out of 83 participants, 71 cases (85.5%) were males and 12 (14.5%) were females. Their age range was from 21 to 62 years old. Sixty-nine cases (83.1%) were diagnosed with at least one major psychiatric disorder and 14 cases (16.9%) with none. Among the HIV-infected patients, 54 cases (65.1%) suffered from a mood disorder, 21 (25.3%) had psychotic and 41 (49.4%) had anxiety disorders.Conclusion: The current study showed that major psychiatric disorders were more common in HIV-infected patients in comparison to normal communities, so on-time diagnosis and therapy and proper management of these problems could be truly a promising step in global control of HIV in this part of Iran.

Fibromyalgia (FM) is a chronic musculoskeletal syndrome characterized by pain and fatigue; however, its etiology remains unknown, and various hypotheses and biomarkers have been proposed. This study it is aimed to investigate blood biomarkers in the pathogenesis of FM. The current case-control study has been conducted on 45 females with the documented diagnosis of FM and 45 healthy controls referring to the outpatient clinic of rheumatology in 2018-19. The serum levels of dehydroepiandrosterone (DHEAS), erythrocytic sedimentation rate (ESR), C-reactive protein (CRP), complete blood count (CBC), and thyroid-stimulating hormone (TSH) was measured and compared between the groups. DHEAS serum levels in cases and controls were 27.55±18.80 and 33.55±21.80, (P=0.16), ESR was 29.17±9.75 and 17.37±2.82 (P<0.001), CRP was 4.17±1.53 and 3.53±1.15 (P=0.02), TSH was 3.307±0.27 and 3.41±0.22 (P=0.09), respectively. The two groups were similar in CBC indices, including hemoglobin, hematocrit, white blood cell, lymphocyte, neutrophil, and platelet count (P>0.05). DHEAS was slightly, but insignificantly, lower among the females with FM than healthy cases. On the other hand, the serum ESR and CRP levels were remarkably higher among the females with FM; however, in the normal range, a fact representing the possible traces of inflammation in the pathogenesis of FM.