Background: The objective of the study was to evaluate the prevalence of thyroid dysfunction in dysfunctional uterine bleeding and to assess the menstrual and endometrial pattern in women with thyroid disorders.Methods: The present study was conducted on 200 patients who presented with dysfunctional uterine bleeding in gynecology OPD.Results: Among the 200 women 39 (19.5%) had hypothyroidism, 2 (1%) had hyperthyroidism and 159 (79.55%) were euthyroid. Menorrhagia was the most common menstrual disorder in hypothyroidism and oligomenorrhoea in hyperthyroidism. In the present study 74.3% patients had proliferative endometrium,26.3% secretory endometrium, in hypothyroid patients and secretory endometrium in 2 (1%) hyperthyroid patients. A woman with hypothyroidism, commonly presents with anovulation and unopposed oestrogen activity causes endometrial hyperplasia which may outgrow the blood supply and may cause local areas of necrosis and breakdown and produces bleeding.Conclusions: The menstrual irregularities are significantly more frequent in patients with thyroid dysfunction and menorrhagia was the commonest menstrual abnormality. The study concludes that biochemical evaluation of thyroid function should be made mandatory in all cases of abnormal uterine bleeding and this would avoid unnecessary surgeries and exposure to hormones.

Background: The objective of the study was to review the impact of thyroid status on the fertility and to study the prevalence of hyperprolactinaemia in infertility.Methods: A total of 150 subjects were divided into 3 groups: 50 primary infertility, 50 secondary infertility and 50 controls. The incidence of hyperprolactinaemia and thyroid disorders was studied in all the three groups.Results: The incidence of hyperprolactinaemia was 41% in all infertile subjects (60% with primary and 22% in secondary infertility) and 6% in controls. The incidence of hypothyroidism was 17% in infertility (18% in primary and 16% in secondary infertility) and 8% in controls.Conclusions: In this study there is a positive correlation between increased prolactin levels and hypothyroidism and such patients’ exhibit ovulatory failure. All patients with infertility should undergo prolactin levels and thyroid profile.