During the COVID-19 pandemic, numerous swab samples have been taken for SARS-CoV-2 reverse transcriptasepolymerase chain reaction (RT-PCR) testing. Nasopharyngeal sampling is considered safe, despite adjacent vital structures (eg, orbit, skull base, rich vasculature; Figure). However, single case reports [1][2][3][4] and clinical observations indicate the possibility of severe complications. This case series investigated the frequency and type of SARS-CoV-2 nasopharyngeal test complications.Methods | All patients presenting to the dedicated otorhinolaryngology emergency department

In rodents, the Robo1 gene regulates midline crossing of major nerve tracts, a fundamental property of the mammalian CNS. However, the neurodevelopmental function of the human ROBO1 gene remains unknown, apart from a suggested role in dyslexia. We therefore studied axonal crossing with a functional approach, based on magnetoencephalography, in 10 dyslexic individuals who all share the same rare, weakly expressing haplotype of the ROBO1 gene. Auditory-cortex responses were recorded separately to left-and right-ear sounds that were amplitude modulated at different frequencies. We found impaired interaural interaction that depended on the ROBO1 in a dosedependent manner. Our results indicate that normal crossing of the auditory pathways requires an adequate ROBO1 expression level.

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