Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. Currently, several diagnostic modalities are available for COVID-19, each with its own pros and cons. Although there is a global consensus to increase the testing capacity, it is also essential to prudently utilize these tests to control the pandemic. In this paper, we have reviewed the current array of diagnostics for SARSCoV-2 highlighted the gaps in current diagnostic modalities and their role in community surveillance and control of the pandemic. The different modalities of COVID-19 diagnosis discussed are: clinical and radiological, molecular-based (laboratory-based and point-of-care), Immunoassay based (ELISA, rapid antigen and antibody detection tests) and digital diagnostics (artificial intelligence-based algorithms). The role of rapid antigen/antibody detection tests in community surveillance has also been described here. These tests can be used to identify asymptomatic persons exposed to the virus and in community-based seroprevalence surveys to assess the epidemiology of spread of the virus. However, there are few concerns about the accuracy of these tests which needs to evaluated beforehand.

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by cobalt(IX), zinc, cadmium, mercury, alumim'um, iron(III), palladium.Procedure [or the Titration. Adjust the pH of 5 ml of 0.05 M EDTA solution to 7.0 by adding 10.0 ml of sodium acetate/acetic acid buffer, add 10.0 ml of 1,4-dioxane to keep ligand and complex in solution, followed by two drops of QAP solution (0.349 g/100 ml freshy distilled 1,4-dioxane). Titrate slowly with the copper sample solution, shaking after the addition of each drop. l~ear the end-point wait 30 see after each drop. A sharp eolour change from yellow to blue will be obtained.

Ruthenium, rhodium, palladium, osmium, iridium and platinum have been separated from a single spot in horizontal paper electrophoresis using ethylenediaminetetetic acid (EDTA) aa background electrolyte.Electrograms were run ueing 0.01 M electrolyte, at pH 9.0, 106, 11.0 and 12.0. Binary, ternary, quaternary and quinary separations are possible at various p H values, but best separation occurs at pH 110. At this pH, ruthenium and osmium slightly overlap with each other and can be separated by cutting this zone and placing it on a fresh paper and carrying on the electrophoresis, now using 0.1M EDTA at pH 6.0. Ruthenium and osmium can thus be separated from each other on the second paper, The temperature is kept at 20°C, a potential 250 V is supplied, and the developing time is 36 hr.The electrophoretic separation of platinum metals has been attempted by various workers ( 1 4 ) using disodium salt of ethylenediaminetetraacetic acid (EDTA) as background electrolyte, but no success has been achieved for the separation of all six platinum metals when present together in a mixture, using paper electrophoresis. Ghose and Dey ( 6 ) , however, from these laboratories, could separate the six platinum metals by paper chromatography.The present communication describes the separation of all six platinum metals from a single spot, using EDTA as background electrolyte at pH 11.0 and 6.0. A very simple technique has been devised to separate the overlapped spot by transfer from one paper to another and subjecting to electrophoresis under a new set of conditions.