A peptic ulcer is common gastrointestinal disorder. Peptic ulcers are sores on the stomach, small intestine, or esophageal lining. It is caused by H. pylori infection regular usage of NSAID’s, irregular food habits, stress, Gastric Acid Secretions. Various synthetic drugs are available for the treatment of peptic ulcer. But these are expensive and produce more side effects as compared to herbal drugs. The literature revealed that many herbal drugs and polyherbal formulations are used in the treatment of peptic ulcer. In this review is a compilation of knowledge gathered from the research papers published and review the various herbal drugs and polyherbal formulation used for peptic ulcer.