Background: Iron deficiency anemia is common problem in children, though the oral iron therapy is the main stay of treatment, but most of children not responding to it due to non-compliance. So the parental iron therapy is the treatment of choice for it. Methods: Fifty children between the age group of 1-17 years of age were selected for this study diagnosed as iron deficiency anemia. Iron sucrose given by IV according to their weight and age. CBC performed before starting of study and after receiving Iron sucrose intravenously i.e. after 4, 10 and 30 days of iron sucrose. Results: Among the red cell indices, mean corpuscular volume and mean corpuscular haemoglobin in this study we got mark improvement in both the parameters along with improvement in PCV and finally increase in haemoglobin level. All the parameters having P value highly significant i.e. <0.001 along with minimal side effects. Conclusions: Iron sucrose can be safely used in children.