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Progressiv,e hypertrophic polyneuiritis is a (lisease whicil may be manlifest at aniy age and is often-familial. The main feature is thickeniing of the peripheral nerves, which are often palpable and which present characteiristic histological changes. There is muscullar atrophy of the feet or hands, or of both, but it is usuially more marked in the feet. The condition tends to be progressive and the muiscles of the proximal parts of the limbs may be affected later. Deformities frequently arise, of which pes cavus, claw-hand and kyphoscoliosis are the most common. Dimninution or absence of the tendon reflexes is the rule and sensory changes are not infrequent.French authors have endeavoured to classify the disease into types.

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