Objective: To analyze the histopathologic outcomes of patients with atypical glandular cells (AGC) in cervicovaginal cytology examinations.
Material and Methods:Patients with AGC in cervicovaginal cytology were included in this study between March 2011 and March 2018 and patient data were collected retrospectively among all cytology results. AGC classification of cervicovaginal cytology were based on the Bethesda 2001 classification system.
Results:The total prevalence of cervical epithelial cell abnormality and AGC were found as 4.2% and 0.2%, respectively, in the study cohort.AGC-favor neoplasia (AGC-FN) was the subgroup of AGC with the highest malignancy rate with 62.5% (p=0.06). The incidence of malignancy in the postmenopausal group (33.3%) was detected higher than in the premenopausal group (8.3%) (p=0.07).
Conclusion:The probability of malignancy in AGC-FN cytology is more commonly associated with malignancy in the postmenopausal group.Therefore, histopathologic examination is strongly recommended in these patients with AGC smears because of the high risk for malignancy in this group. (J Turk Ger Gynecol Assoc 2020; 21: 102-6)
21st.Century witnesses enormous technological development effecting Architecture also: New and improved building materials and construction techniques, highly innovative development of structural systems utilizing advanced computer software leads to significant novelties in built environment, worldwide. The 'Diagrid Structure', having a hyperboloid form, of which the first design and implementation was applied by V. Shukhov in, as early as, 1896. Both due to diagrid and to its doubly curved form, it proved to achieve greater lateral strength, rigidity and efficiency than rectangular frame system, decreasing the amount of the required material, besides offering the possibility of prefabrication and ease of assembly. Although the first diagrid structure was built in 1963-the IBM building in Pittsburgh-it did not utilize a doubly curved form. The system was not widely recognized until the Gherkin Tower designed by Sir N. Foster was completed in London, in 2003, displaying the twinning of architectural and structural design.
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