The aim of this paper is to present the incidence of placental abruption and placenta previa at GAO General Hospital N. Pazar like to stress the importance of bleeding in the second trimestreu pregnancy. A retrospective study was conducted at the department of gynecology and obstetrics, ZC Novi Pazar January 2008 December 2012th As the basis of the data, the history and the findings from the protocol konzervtaivno treated surgically and we pacijenata. Analizirali incidence of bleeding compared to the total number of births, maternal age, parity and gestation. During the period of 2008-2012, there were 186 abruption (1.72 %) and 34 placenta previa (0.31%). Within a given period, there were 10778 delivery of which 220 bleeding or 2.03 %. The incidence of placenta previa and ab.placente compared to 84.5% abruption and placenta previa 15.5%. The age of pregnant women who develop bleeding: the highest percentage of bleeding at the age of 26-31god (43.6%) than in the group of 19-25 years. 82.63 % and the lowest in the group under 18 (3.18) and above 35 years of age (11.3%). Maternal parity. primipara i 92 (41.88%), second child 49 (22.27 %) , third child i 46 (20.91%), fourth child 28 (12.72%). Gestational age at which it contacted the bleeding; 8 to 27 ng (3,645), 28-34 ng 30 (13.63 %) 0.35 to 37 ng 41 (18.64 %), and 37 ng 141 (64%). Method of delivery; caesarean 117 abruption (62%) vaginal delivery 69 (38%). Placenta previa; cesarean section 28 (82.3 %) and 6 vaginal (17.6 %). Any bleeding in the second half of pregnancy should be taken seriously. Prolong pregnancy as possible. You need to pay attention to risk factors: hypertension, gestational diabetes, smoking, previous cesarean section, and in this sense preventive effect on pregnant women.

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Trisomy 13 (Sy Patau) is a clinically severe entity. 85% of the patients do not survive beyond one year, and most children die before completing six months of age. We report a female child, 30 day old, white, the third child of a non-consanguineous couple, who presented trisomy 13. The child was born at term, from a vaginal delivery, weighing 3200 g. The second day of life the development of respiratory distress translated ino KBC Kragujevac (release list no.29623). The initial clinical examination detected shisis primariy and secunday palate, ASD, stenosis rami AP, polidactily pedis dextri, microcornea and microftalmia. After 27 days of hospitalization in KBC Kragujevac, transferred to the Institute for mother and child New Belgrade, where he died after three days of receipt. During hospitalization blood samples were taken for determination of kariotip. Parents are advised that in case of subsequent pregnancies occur in the genetic counseling of the Institute for prenatal diagnosis. ApstraktTrizomija 13 (Patau sindrom) je ozbiljan klinički entitet. 85% pacijenata ne preživi duže od godinu dana, a većina umire pre nego što napuni šest meseci. Mi prikazujemo žensko novorođenče, uzrasta 30 dana, treće dete iz kontrolisane trudnoće, koje je imalo trizomiju 13. hromozoma. Dete je rođeno u terminu, vaginalnim putem, težine 3200 grama. Drugi dan života razvija respiratorni distres, pa je prevedeno u KBC Kragujevac. Na prvom kliničkom pregledu konstatovan je rascep primarnog i sekundarnog nepca, ASD, stenoza rami AP, polidaktilija desnog stopala, microcornea i microftalmia. Posle 27 dana hospitalizacije u KBC Kragujevac, prebačeno je u Institut za majku i dete Novi Beograd, gde je umrlo posle tri dana od dana prijema. Tokom hospitalizacije uzet je uzorak krvi za određivanje kariotipa. Roditeljima je savetovano da u slučaju ponovnih trudnoća dođu u genetičko savetovalište Instituta za prenatalnu dijagnostiku.Ključne reči: Patau syndrom, trizomija 13, hromozomopatija, novorođenče. UvodTrizomijа 13 (tаkođe poznаtа kao Pаtаu sindrom) je genetski poremećаj u kome osobа imа tri kopije genetskog mаterijаlа na hromosomu 13, umesto uobičаjenih dvа primerkа. Retko, ekstrа mаterijаl može biti vezаn zа drugi hromozom (trаnslokаcija) 1 .Sindrom je otkrio i opisao prvi put Klaus Patau (Klaus Patau) 1960. godine. Označava se 47 XX+13 ili 47 XY+13, u zavisnosti od pola 1 . Učestalost sindroma je oko 1:8000 -12000 zivorođenčadi. Specifičan etiološki faktora za nastanaka ovog sindroma nije nađen, ali postoji značajna povezanost sa starošću porodilja. U normalnim somatskim ćelijama čoveka broj hromozoma je 46, a u malom broju slučajeva, oko 5%, može se javiti i tzv. mozaicizam, pri kome postoje dve ćelijske linije: jedna sa normalnim brojem hromozoma, a druga sa trizomijom hromozoma 13. Obično su ovakve osobe sa blažim simptomima i lakšim oblikom bolesti 2,3 .Poremećaj se manifestuje multiplim anomalijama: rascep usne, vilice i nepca (heliognatopalatoshiza), mentalna retardacija, polidaktilija, pupčana i preponska kila, mala gla...

In this manuscript we report one pediatric surgeon's experience in childhood inguinal hernia repair. From 2005 to 2008, 402 children with inguinal hernias were operated on by one surgeon. A retrospective survey of their charts was carried out to evaluate the demographics and clinical aspects of these patients. The ages ranged from 20 days to 16 years with a maleto-female ratio of 2.5:1. 64.9% right, 27.1% left, and 7.9% bilateral hernias. Hydroceles were present in 6.2% assosiated hernias. Incarceration occurred in 8.7% of children. An opposite-side hernia developed in 5.7%. 5.3 percent of patients with a hernia repair on the right side later developed a hernia on the left side, and 8.2% of patients with a hernia repair on the left side later developed one on the right side. 4.5 percent of all male patients in this series and 8.6% of female patients developed an opposite-side hernia. While overall recurrence rate was 1.2%, our recurrence rate was 0.25%. There was a 0.24% wound infection rate, and 1 (0.24%) testicle was atrophic at followup. In this study, in the recurrence of childhood hernia, the general surgeon's intervention was the prominent cause. It is suggested by the study that inguinal hernias on the contralateral side becomes symptomatic within the first six months following initial operation.Therefor, close observation is needed in that time. U period od 2010. do 2014. godine, na odeljenu dečije hirurgije Z Novi Pazar operisano je 401 dece od preponske kile od strane tri dečija hirurga. Retrospektiva analiza njihovih grafikona i tabela je sprovedena radi procene kliničkih aspekta operisanih pacijenata. U starosti se kretale od 20 dana do 15 godina sa muško-to-ženska odnosu 2,5: 1. 64,9% u pravu, 27.1% levo, a 7,9% bilateralni kile. Hidroceles bili prisutni u 6.2% assosiated kile. Zatvaranje desilo u 8,7% dece.Suprotnoj strani hernija razvijen u 5,7%. 5.3 odsto pacijenata sa kile na desnoj strani kasnije razvio kilu na levoj strani, a 8,2% pacijenata sa kile na levoj strani kasnije razvio jedan na desnoj strani. 4.5 odsto svih muškaraca obolelih u ovoj seriji i 8,6% od pacijentkinja razvio naprotiv-side kilu. Dok ukupna stopa recidiva je 1,2%, naša stopa recidiva je 0,25%. Bilo je infekcija stopa 0,24%, a 1 (0.24%) testis je atrofični na praćenje. U ovoj studiji, smo pokazali da u odnosu na druge studije jako je važno da pedijatrijske pacijente operisu iskljucivo pedijatrijski hirurzi jer je broj postoperativnih komplikacija i recidiva kile jako mali. Obzirom da se recidivi i pojave kile na kontralateralnoj strain javljaju najviše u prvih 6 meseci nakon operacije, bitno je češće decu kontrolisati u tom periodu.Ključne reči: Dečja ingvinalna kila, recidiv, procesus vaginalis, operacija UvodPreponski kila je najčešća indikacija za operaciju u pedijatrijskoj starosnoj grupi i učestalost preponske kile u tim mlađi od 18 godina varira od 0,8 do 4,4% 1 . Svi pedijatrijski ingvinalni kile zahtevaju operativno lečenje da bi se sprečio razvoj komplikacija, kao što su inkarceracijia , ili strangulacija 2...

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