Background: Gastric cancer is the 2nd most common cause of cancer-related deaths, and the morbidity rate after surgery is reported to be as high as 46%. The estimation of possible complications, morbidity, and mortality and the ability to specify patients at high risk have become substantial for an intimate follow-up and for proper management in the intensive care unit. This study aimed to determine the prognostic value of the preoperative platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) and their relations with clinical outcomes and complications after gastrectomy for gastric cancer. Methods: This single-center, retrospective cohort study evaluated the data of 292 patients who underwent gastrectomy with curative intent between January 2015 and June 2018 in a tertiary state hospital in Ankara, Turkey. A receiver operating characteristic curve was generated to evaluate the ability of laboratory values to predict clinically relevant postoperative complications. The area under the curve was computed to compare the predictive power of the NLR and PLR. Then, the cutoff points were selected as the stratifying values for the PLR and NLR. Results: The area under the curve values of the PLR (0.60, 95% CI 0.542-0.657) and NLR (0.556, 95% CI 0.497-0.614) were larger than those of the other preoperative laboratory values. For the PLR, the diagnostic sensitivity and specificity were 50.00 and 72.22%, respectively, whereas for the NLR, the diagnostic sensitivity and specificity were 37.50 and 80.16%, respectively. The PLR was related to morbidity, whereas the relation of the NLR with mortality was more prominent. This study demonstrated that the PLR and NLR may predict mortality and morbidity via the Clavien-Dindo classification in gastric cancer patients. The variable was grade ≥ 3 in the Clavien-Dindo classification, including complications requiring surgical or endoscopic interventions, life-threatening complications, and death. Both the PLR and NLR differed significantly according to Clavien-Dindo grade ≥ 3. In this analysis, the PLR was related to morbidity, while the NLR relation with mortality was more intense. Conclusion: Based on the results of the study, the PLR and NLR could be used as independent predictive factors for mortality and morbidity in patients with gastric cancer.

Background and aim: Creating potential clinical markers for risk assessment in patients with COVID-19 continues to be an area of interest. In this study, we aimed to evaluate whether serum albumin level and thrombocyte/lymphocyte ratio are related to the severity of the disease. Materials and methods:The patients were divided into two groups according to the severity of disease. Demographic data, serum albumin value, lymphocyte count, TLO-1 values (thrombocyte/lymphocyte ratio-1), the highest thrombocyte count during hospitalization, TLO-2 (thrombocyte/lymphocyte ratio-2) values formed by the highest thrombocyte count, were recorded.Results: There was no statistically significant differences (P > 0.05) in terms of sex, thrombocyte count at the time of admission, and highest thrombocyte count during hospital follow-up. There were statistically significant differences in terms of age, comorbidity, lymphocyte value at the time of hospitalization, lymphocyte count during hospital follow-up, TLO 1, TLO 2, and serum albumin values between the groups. The ICU group were found to be older, had higher rates of comorbidity, lower lymphocyte values, higher TLO 1-2, and lower serum albumin levels (P < 0.05). Conclusion:TLO-2 ratio above 260 and lymphocyte level below 1 103 cells/µL, would be a predictor of further intensive care unit need.

In the original publication of this article [1] there are two garbled codes in the second sentence, the fourth paragraph of the Background section. The correct sentence should be: Tumor growth leads to the increased production of inflammatory cytokines and growth factors (mainly IL-1, IL-3, IL-6, IL-11, IL-23, and TNF-), and this perpetual process ensures immortality. These promoting factors are also important for angiogenesis and hematopoiesis, which explains the increase in blood cell types in cancerous diseases. The original publication has been corrected.

Subtotal özofajektomi mide serbestleştirilmesi sonrası torakotomi ile özofajektomi ve özofagogastrik anastomozu içerir. Özofagus karsinomunda, yüksek dereceli displazide, kostik özofageal yaralanmalarda uygulanabilir. Bu operasyon sonrası atelektazi, pnömoni, aspirasyon ve uzamış entübasyon gerektiren solunum yetmezliği pulmoner komplikasyon olarak görülebilir. Pulmoner komplikasyonların oranı %20 ile %50 arasında değişmektedir. Pulmoner komplikasyon gelişimi hastanede kalış süresini uzatmanın yanı sıra mortalite ve morbiditeyi anlamlı oranda arttırmaktadır. Bu çalışmada postoperatif pulmoner komplikasyon gelişen 5 olguyu retrospektif olarak değerlendirdik. Olguların postoperatif dönemde 4 tanesinde pnömoni, 1'inde atelektazi, 1'inde pnömotoraks ve cilt altı amfizem geliştiği saptandı. Bir hasta postoperatif dönemde anastomoz kaçağına bağlı exitus oldu. Dikkatli bir preoperatif değerlendirme ve uygun postoperatif önlemler ile pulmoner komplikasyon oranları azaltılabilir. Bu çalışmada özofagus cerrahisi sonrası postoperatif pulmoner komplikasyon gelişen olguları değerlendirmeyi amaçladık.

Trakea-özofageal fistül, özofagus ve trakea arasında bağlantı olmasıdır. Konjenital veya edinsel olarak oluşabilirler. Erişkinlerde çoğunlukla edinsel şekli görülür. Trakea-özofageal fistül hayatı tehdit eden bir durum olup uygun yöntemle tedavi edilmesi gerekir. Bu olgu sunumunda Ivor Lewis ameliyatı nedeniyle takip edilen hastada özofagusa stent uygulanması sonrası stent migrasyonuna bağlı gelişen trakeözofageal fistül olgusu sunulmuştur.