Patients with cholelithiasis are treated by the method of extracorporeal lithotripsy. The technique of the combined use of two lithotriptors with different modes of shock wave generation (electrohydraulic and electromagnetic) is described. As a result of treatment the number of skin petechiae decreases as do transitory hematuria and manifestations of hepatic colic and acute panereatitis, whereas mechanical jaundice and acute cholecystitis develop with the same frequency. The number of recurrences of cholelithogeny in patients with hyperlipidemia is 8 times higher than in the control, which indicates a clear connection between hyperlipidernia and stone formation in patients after extracorporeal biliary lithotripsy. Key Words: cholelithiasis; extracorporeal biliary lithotripsy; hyperlipoproteinemiaExtracorporeal biliary lithotripsy (ECBL) has proven to be a rather effective and sparing treatment of cholelithiasis. We showed that ECBL is the treatment of choice for some 15% of patients with gallstones. Successful treatment with ECBL depends on a careful choice of patients who are to undergo the procedure. Candidates were chosen on the basis of ultrasound scanning as well as findings of peroral cholecystography in addition to a general clinical examination. This allowed us to work out clear guidelines for selecting patients to undergo ECBL.We used two lithotriptors with different modes of generation of shock waves (electrohydraulic and electromagnetic) to achieve a favorable combination of these apparatuses, which are considered comparable in terms of the intensity of the shock wave [4,7,10,11]. It was noted, however, that the Sonolith 3000 possesses a more powerful destructive ability.Analysis of the long-term results of the treatment revealed that new stones form in 23% of pa-