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Background/Aims: Helicobacter pylori affects many individuals in developing countries. Inflammation caused by helicobacter pylori differs depending on the virulence factors, density and host tissue response of the bacteria. This study is intended to investigate the relation between density of helicobacter pylori colonization in gastric mucosa in biopsy specimens and gastric mucosal inflammation severity. Materials and methods: Our study included 685 patients who applied to the hospital with dyspeptic complaints and had gastroscopy between the dates of January the 1 st 2017 and January the 1 st 2018. Histopathologic results of endoscopic biopsy specimens of these patients were retrospectively screened. Inflammatory severity and helicobacter pylori intensity were assessed by Sydney scoring. Results: 68.6% of the patients were infected with Helicobacter pylori. As the intensity of inflammation increased, the intensity of Helicobacter pylori increased as well. The relation between the intensity of Helicobacter pylori and the severity of inflammation was statistically significant (p < 0.001). Conclusion: Helicobacter pylori infection increases gastric inflammation.

Öz Purpose: In our study, we aimed to determine the anxiety and depression risks of patients with type 2 diabetes who have an important public health problem in the world and in Turkey and to determine the conditions related to these risks. Materials and Methods: This cross-sectional analytical study was performed in 636 patients with type 2 diabetes who presented to the Internal Diseases Clinic. A questionnaire form prepared by the researchers was used for sociodemographic data. The Hospital Anxiety and Depression Scale (HADS) was used to determine the anxiety and depression risks of the patients. Results: 59.9% (n = 381) of the participants were female and 40.1% (n = 255) were male and the mean age of the whole group was 59.98 ± 11.66 years. The risk of anxiety was found in 48.4% (n = 308) of the participants and the risk of depression was found in 67.3% (n = 428). The risk of anxiety and depression was significantly higher in women aged 60 and over, in women, in primary and lower education, in housewives or retired, in patients with comorbid diseases and in those receiving insulin therapy. It was significantly lower in married and smokers. Conclusion: The risk of anxiety and depression was found to be high in patients with Type 2 diabetes. This risk was associated with age, sex, marital status, education, occupation, comorbidity and diabetes treatment. Patients with high risk for anxiety and depression should be treated with the psychiatry department.

Öz Huzursuz bacak sendromu (HBS) bacaklarda hareket etme dürtüsü ile kendini gösteren, şikayetlerin istirahatte arttığı, bacaklarda rahatsızlık veren duyumlar ile karakterize uyku ilişkili bir hastalık olarak tanımlanmış nörolojik duyusal-motor bir bozukluktur. Hastalığın primer (idiyopatik) HBS ve sekonder (semptomatik) HBS olmak üzere iki formu vardır. İdiyopatik form genetik ve kaynağı bilinmeyen etiyolojik nedenleri içerirken, sekonder formun çok çeşitli sebepleri olabilir. Sekonder HBS'nin etiyolojik sebepleri değerlendirildiğinde %43' ünün anemi ile birlikte veya anemi olmaksızın sistemik demir eksikliği ilişkili olduğu tespit edilmiştir. Bu yazıda; son 2 yılda 8 kez tam kan bağışında bulunan ve ferritin düşüklüğüne atfedilen sekonder HBS' lu bir olgumuzu sunduk.