The obtained results revealed that minocycline has anticonvulsant effect on seizures induced by amygdala kindling. Thus, it may be useful for epilepsy treatment.

Introduction: Regular exercise training has been shown to be a useful option to treat and prevent type 2 diabetes. Correspondingly, the purpose of this study was to investigate effects of 12 weeks of combined aerobic-resistance exercise training on levels of chemerin, omentin and insulin resistance in men with type 2 diabetes.Materials and Methods: In this clinical trial research, 20 male patients with type 2 diabetes were randomly divided into two groups combined aerobic-resistance training (n=10) and control (n=10). Subjects in training group performed 12 weeks aerobic-resistance training, 3 weekly training sessions with given intensity (aerobic: intensity of 60-70% maximum heart rate resistance: intensity 60-70% repetition maximum). Blood sampling was taken measurements of for chemerin, omentin resistance, fasting glucose and insulin resistance in the beginning and after 12 training protocol weeks were conducted.Results: After 12 weeks, in the combined training group chemerin (p=0.01), resistance insulin (p=0.01) and fasting glucose (p=0.001) decreased significantly and Vo2max increased significantly (p=0.001) than the control group. Significant change was not observed at the levels of omentin (p=0.37).Conclusion: 12 weeks of aerobic-resistance training in men with type 2 diabetes decreased the levels of chemerin, insulin resistance and also fasting glucose, but did not affect the level of omentin.

Cytisus scoparius L. is a plant commonly grown in parks, on highway margins, and in urban green spaces due to its beauty and flowers. It belongs to the family Fabaceae. The allergenicity of its pollen grains has been demonstrated (Majd & Rezanejad,2004); however,the allergenicity of thevery fragrant petals and its severitycompared withthat of maturepollen grains are unclear. Therefore, our aim was to investigate the allergenicity of pollen grain sand extremely fragrant petal songuinea pigs. In this study, buffered mature pollen extract and buffer extracts of petals at two ontogenic stages of old and middle-aged plants were prepared at a concentration of 16% and injected intra peritoneally and subdermally into guinea pigs. After the injection of extracts into the peritoneumfor 5 weeks, at 1-week intervals, blood samples were collected from the animals, and the levels of blood sugar, eosinophils, and serum IgE were measured. Clinical tests showed that the most potent stimulator of the immune system was the pollen extract, followed by the petal extract of middle-aged plants and old petal extract. In addition, electrophoretic profiles revealed approximately six specific protein bands that ranged from 15 to 85 kDa in the soluble pollen protein fraction, four protein bands between 27 and 85 kDa in the soluble fraction of middle-aged petal proteins, and approximately three faint protein bands between 45 and 85 kDa in the soluble protein fraction of old petals.