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Introduction: This study was designed to evaluate the effects of treatment with flaxseed oil (FSO) on renal ischemia-reperfusion (RIR) injuries in rats. Materials and methods: In this study, 32 Wistar rats were randomly studied in four groups: Co+NS (Control group with normal saline administration), Sh+NS (sham group with normal saline administration), RIR+NS and RIR+FSO. FSO (0.2 ml) was administered orally (gavage) for 14 days (~ 800 mg/kg body weight). Blood samples were collected for the detection of blood urea nitrogen (BUN) and creatinine levels. Malondialdehyde (MDA) and superoxide dismutase (SOD) levels were evaluated in the renal tissue. Tubular damages were examined using histopathological studies. Results: Significantly elevated MDA (P<0.05) and depressed SOD levels (P<0.05) Comparison between RIR+NS group and Control+NS and Sh+NS groups revealed in the condition of RIR. Treatment with FSO, however, significantly lowered the MDA (P<0.05) and enhanced SOD levels (P<0.05) after RIR injury. Histopathological results confirmed the biochemical studies and tubular necrosis score was reduced in the RIR+FSO group. Conclusion: This study therefore suggests that the aqueous flaxseed oil may be useful agents for the prevention of renal ischemia-reperfusion (RIR)-induced oxidative injury in rats.

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Introduction: Urinary Incontinence (UI) is a common problem in obese women affected by different parameters such as weight, Body Mass Index (BMI), type of delivery, etc. This study aimed to investigate the relationship between the lumbar lordosis, anthropometric characteristics, and the incidence of urinary incontinence in obese women. Materials and Methods: This cross-sectional study was conducted on 193 obese women (BMI>30 kg/m 2) with and without UI. Anthropometric characteristics and lordosis angle were measured in participants, and then they were asked to fill out demographic information and urinary incontinence questionnaires. The obtained data were analyzed by SPSS V. 23 using statistical tests, including the Independent t test, Spearman correlation, and logistic regression. Results: Women who suffered from UI had a lower lumbar lordosis angle, were younger, and shorter, with a higher number of natural deliveries. Discussion: Based on the findings of this study, a direct relationship exists between natural delivery and UI. However, an indirect relationship is observed between UI and age, lumbar lordosis angle, and height. Because of the effect of lumbar lordosis on the incidence of urinary incontinence in obese people, spine alignment, and changes in abdominal biomechanical parameters might also have an impact on UI.