The interaction between teams behaviour is from high relevance for success in sports games. Since the analysis of this interaction is not well established, the present study attempts to model the interaction between opposing teams in team handball. Offensive and defensive playing patterns were determined by means of artificial neural networks from position data of 723 offensive action sequences and the corresponding defensive players, respectively. The most common combinations of these patterns were then analysed statistically. Pattern efficiency was assessed by scoring rate, distance between shooting position and nearest defensive player and distance to goal. No statistically significant relation between pattern combinations and efficiency was found. However, results revealed tendencies to higher efficiency of some tactical patterns. Furthermore, odds ratio analysis revealed advantageous defensive tactics against specific offensive behaviour. Summarizing, results indicate that artificial neural networks are appropriate to model the interaction between teams based on players' positions. ARTICLE HISTORY