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BackgroundHypertensive disorders are common during pregnancy, and are among 3 important causes of maternal death. Preeclampsia occurs in 3 to 5% of pregnancies. Early diagnosis of this disorder can lead to better pregnancy outcomes.ObjectiveThe aim of this study was to determine the relationship between inhibin A serum levels during second stage pregnancy screening tests, and incidence and severity of preeclampsia.MethodsIn this study, 300 pregnant women who referred to Kowsar Hospital and carried out second stage pregnancy screening tests from September 2014 to March 2015 in Urmia city, Iran, were enrolled. Five ml venous blood samples were obtained from each participant, and inhibin A serum levels were evaluated in all cases. Finally, all the necessary information was obtained from the pregnancy files of participants after delivery, and gathered in a questionnaire. The data were analyzed using SPSS software version 18 and independent t-test, ANOVA and descriptive statistics were used. P-values less than 0.05 were considered significant.ResultsAmong the 300 pregnant women who were studied, the gestational age at the time of acquiring blood samples was as follows: 169 cases (56.3%) at 16–17 weeks, 77 cases (25.7%) at 18–19 weeks and 14 cases at 20 weeks (4.7%). In this study, MOM of inhibin A was more than 1.25 in 12 cases that finally, preeclampsia occurred in them. This relationship was statistically significant (p=0.001). The relationship between MOM of inhibin A and severe preeclampsia was evaluated, and the relationship was significant (p=0.004). The relationship between MOM of inhibin A and pregnancy hypertension was not significant (p=0.643).ConclusionConsidering the results of this study, we can conclude that MOM of inhibin A levels in maternal serum during second stage pregnancy screening tests can predict incidence and severity of developing preeclampsia in pregnant women. This is not true in cases of pregnancy hypertension.

Background: Traffic events are the second most common cause of mortality and the first cause of years of life lost (YLL) in Iran. Objectives: The aim of this study was to determine the survival of patients with traffic injury and evaluate hospital care quality using the trauma and injury severity score (TRISS) method. Methods: This cross-sectional study was conducted on 1000 patients aged 1 to 89 years old who were hospitalized in two university hospitals in East Azerbaijan, Iran. Patients were selected by using stratified sampling. Data were extracted from medical records and analyzed by STATA11 software. Injury severity score (ISS), revised trauma score (RTS), and expected survival were calculated using the TRISS software package. W-scores and Z-scores were calculated to evaluate the performance of hospitals. Finally, results were compared to those of the major trauma outcome study (MTOS). Results: Among 1000 patients, 246 (24.6%) were female. The mean age was 32.6 years (SD, 18.6). Mean ISS for living patients was 12.4 (SD, 4.3) while it was 36.9 (SD, 8.9) for fatal cases. The average RTS was reported to be 7.1 and 4.35 for alive and fatal cases, respectively (P < 0.001). Based on TRISS, 58 cases were expected to result in death; however, 65 fatalities were observed (65/1000). The W-score was -7 per 1000 and Z-score was + 0.02. The TRISS misclassification rate for survival status of patients with traffic injury was reported as 2.6%. Conclusions: Our findings indicate that the quality of care at the hospitals under study using the TRISS method was lower than the quality of care in the MTOS study. Further, survival of traffic injury patients was clearly influenced by the quality of hospital services provided.

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