A new generation of precipitation measurement products has emerged, and their performances have gained much attention from the scientific community, such as the Multi-Radar Multi-Sensor system (MRMS) from the National Severe Storm Laboratory (NSSL) and the Global Precipitation Measurement Mission (GPM) from the National Aeronautics and Space Administration (NASA). This study statistically evaluated the MRMS and GPM products and investigated their cascading hydrological response in August of 2017, when Hurricane Harvey brought historical and record-breaking precipitation to the Gulf Coast (>1500 mm), causing 107 fatalities along with about USD 125 billion worth of damage. Rain-gauge observations from Harris County Flood Control District (HCFCD) and stream-gauge measurements by the United States Geological Survey (USGS) were used as ground truths to evaluate MRMS, GPM and National Centers for Environmental Prediction (NCEP) gauge-only data by using statistical metrics and hydrological simulations using the Ensemble Framework for Flash Flooding Forecast (EF5) model. The results indicate that remote sensing technologies can accurately detect and estimate the unprecedented precipitation event with their near-real-time products, and all precipitation products produced good hydrological simulations, where the Nash-Sutcliff model efficiency coefficients (NSCE) were close to 0.9 for both the MRMS and GPM products. With the timeliness and seamless coverage of MRMS and GPM, the study also demonstrated the capability and efficiency of the EF5 framework for flash flood modeling over the United States and potentially additional international domains.Remote Sens. 2020, 12, 445 2 of 20 infrastructure, which leads to the intensification of the meteorological extremes [6,7] and increased surface runoff peaks [5]. Globally, the Gulf Coast of North America is one of many places that is heavily affected by tropical storms and their cascading floods in an urbanized area [8]. On August 25th, 2017, Hurricane Harvey made its first landfall at the northern end of San Jose Island, TX. Since then, Harvey stalled over the greater Houston area and produced over 1500 mm of rain in 4 days, which set the US record of total precipitation since the 1880s, when the reliable rainfall records started [9]. During this event, southeast Texas received 20 to 30 trillion tons of water with a return period exceeding 9000 years at some locations [10], interconnected the Colorado River and San Bernard River overland, and caused unprecedented flooding. Hurricane Harvey was estimated to cause about USD 125 billion worth of damage and 107 fatalities, and 127 flash flood warnings were issued during the event [11]. As much as technology has advanced, society is still searching for tools to improve prediction and mitigate the damage from floods.Over the past few decades, the scientific community has made great improvements in the capacity of flood modeling by combining climate models, weather models, hydrological models, river models, and hydrodynamic models [12]....