Nganjuk, Jawa timur adalah daerah penghasil bawang merah, namun potensinya sebagai tanaman obat dan kosmetik belum banyak dikembangkan terutama dalam pemanfaatan senyawa bioaktifnya. Kandungan senyawa bioaktif dinilai berpotensi sebagai zat antioksidan. Tujuan penelitian ini adalah untuk mengetahui senyawa bioaktif dan aktivitas antioksidan dari bawang merah Nganjuk. Ekstraksi sampel menggunakan metode maserasi bertingkat dengan tiga jenis pelarut sesuai kepolarannya, yaitu etanol (polar), etil asetat (semi polar), dan diklorometana (non polar). Jenis pengujian sampel yang dilakukan ialah analisis senyawa bioaktif dan penentuan aktivitas antioksidan menggunakan metode DPPH. Kadar flavonoid menggunakan metode AlCl3 dan untuk penentuan kadar fenolik menggunakan metode Folin Ciocalteu. Hasil penelitian menunjukkan bahwa ekstrak bawang merah Nganjuk mengandung senyawa bioaktif flavonoid, fenolik, saponin, triterpenoid, dan kuinon. Kadar total flavonoid dan fenolik yang didapat rendah yakni secara berturut-turut sebesar 0,881% dan 0,966%. Aktivitas antioksidan ditunjukkan pada nilai IC50 pada ekstrak etanol, etil asetat, dan diklorometana berturut-turut yaitu 384,0341 ppm; 5336,7889 ppm; 884,2754 ppm. Hasil tersebut menunjukkan bahwa aktivitas antioksidan bawang merah Nganjuk sangat lemah karena nilai IC50 >200 ppm. Kata kunci : bawang merah nganjuk, senyawa bioaktif, aktivitas antioksidan

Objective: One of the teaching materials that can increase students' interest and learning motivation is student worksheet with an interesting learning model. This study aims to: (1) train students' argumentation abilities when they want to express their opinions regarding chemical equilibrium material and (2) train students' self-efficacy by bringing opinions related to equilibrium material. Method: The research method refers to the 4D model, namely definition, design, development, and deployment. However, it is only limited to the third stage. The data collection technique used the validation method by three validators, namely two chemistry lecturers and one high school chemistry teacher. The instruments used to assess the validity of the student worksheet are content validity sheets and construct validity sheets. The data obtained is then processed using the agreement percentage formula. Results: student worksheet 1, student worksheet 2, and student worksheet 3 are feasible in terms of content and construction validity with very valid categories. This is evidenced by the agreement percentage value on each student worksheet which is above 75%. Novelty: student worksheet modeled on STEM-integrated ADI will be developed to train students' argumentation skills and self-efficacy. This novelty can be assessed as being able to provide: (1) solutions related to students' interest in ideas on chemical equilibrium material, especially the sub-factors of shifting factors towards chemical equilibrium and (2) being able to increase students' confidence when conveying their ideas or other actions.