No abstract

No abstract

In the four links of mobile phone production, assembly employees account for 60%. In order to improve the assembly efficiency of mobile phone, this paper designed a mobile phone automatic assembly system based on machine vision. The system mainly includes PLC control system, mechanical arm, vision system and touch screen. SIMATIC S7-1200 CPU 1214C is used as PLC controller, and control program is designed.The mobile phone shell, mobile phone chip and screen panel are captured and assembled by DOBOT MG400 four-axis mechanical arm of Yuejiang Technology. Hikvision’s products are selected as the hardware of the vision system, and vision program is designed using DobotVisionStudio algorithm platform of Yuejiang Technology. Vellon’s MT6071IP/MT8071IP (800×400) is the touch screen for the system, and through it, the system can be manually controlled and monitored. Practice has proved that the mobile phone automatic assembly system designed in this paper can perfectly complete the whole process of mobile phone assembly, and the success rate is more than 99%.The mobile phone automatic assembly system based on machine vision has high success rate, high stability, labor saving and long-term operation, which has a certain practical reference significance.

No abstract

Alpinetin, a natural flavonoid found in medicinal herbs, possesses distinct pharmacological activities, including neuroprotective, antiviral, antibacterial, lung and cardiovascular protective, hepatoprotective, antiinflammatory, and antitumor properties. Here, the role of alpinetin was investigated in osteosarcoma. Osteosarcoma cell lines (143B and U2OS) were treated with 10-, 25-, 50-, 75-, or 100-μM concentration of alpinetin. Cell proliferation was detected by cell counting kit 8 (CCK8) and colony formation assays. Western blotting and flow cytometry were used to investigate cell apoptosis. Cell metastasis was assessed by transwell assay. Administration of alpinetin reduced the viabilities of 143B and U2OS cell lines in a dosage-dependent manner, and decreased the number of colonies of 143B and U2OS cell lines. The apoptosis of 143B and U2OS cell lines was promoted by alpinetin through down-regulation of Bcl-2 and up-regulation of cleaved caspase-3 and Bax. Alpinetin inhibited invasion and migration of 143B and U2OS cell lines through up-regulation of epithelial biomarkers, E-cadherin, and zonula occludens-1 (ZO-1), and down-regulation of mesenchymal biomarkers, Vimentin, and N-cadherin. Alpinetin also reduced the phosphorylation of extracellular signal-regulated kinase (ERK), Ak strain transforming (AKT), and phosphoinositide 3-kinases (PI3K) in 143B and U2OS cell lines. Alpinetin inhibited cell proliferation and metastasis in osteosarcoma through inactivation of PI3K/AKT and ERK pathways, providing potential treatment option for treatment of cancer.