Background and Aim: A.marmelos is commonly called as Bael and is used as a medicinal plant mostly in the Ayurveda. Bael has the property of gastrointestinal effect. Bael phytochemicals are radioprotective, chemoprotective and it has efficacious properties in the treatment of cancer and its preventions. The main aim of this study is to estimate an anticancer activity of Bael in colon cancer cells of human. Materials and Methods: Dimethyl sulfoxide (DMSO), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT), Phosphate-buffered saline(PBS) are used as materials. The cell line used is HT 29. MTT test was used to check cell viability by calorimetric technique. The HT 29 cell was exposed to different mediums. Then the cell viability is calculated. Real time PCR was used to analysis gene expression in which cDNA synthesis was performed in varied sample volume. Melting curves were acquired for all samples. Data is analyzed by comparative CT method. It was analyzed by graph pad prism. Results: The findings showed that the effect of Bael fruit extraction of HT 29 cells shows a significance of P<0.05. One of the parameters is treated with untreated control cells. The other two parameters are 100μg, 200μg. In Vimentin mRNA and E cadherin mRNA expression one is treated with untreated control cells and 100μg. Conclusion: This concludes that the properties of the bael can act as an anticancer potential in human colon cancer cell HT 29 through EMT signalling molecules.

Introduction: Mastoid process is a pyramidal bony projection . It is located in the posterior inferior region of the temporal bone. Mastoid notch is on the medial side of the mastoid process. Clinical significance causing infection of the middle ear could spread to the mastoid area causing mastoiditis.  The aim of the study is to determine the morphometric and morphological analysis of mastoid process and mastoid notch in dry human skull and their clinical implication. Materials and Methods: The present study was taken from the department of Anatomy in Saveetha Dental College and Hospital by taking 72 dry human skulls. Digital vernier caliper was used to measure the mastoid process and mastoid notch of different parameters. The data was measured and analyzed statistically, using paired sample ‘t’ tests. Results: The present study shows 0.641 significance in the right and left length of the mastoid process which is not significant. Right breadth and left breadth of the mastoid process of 0.007 and mastoid notch of right and left length 0.00 are significant. Conclusion: It concludes that the mastoid process and mastoid notch have varied significant differences in the dry human skulls. This study will be helpful in mastoid surgeries.