Introduction: Bone grafts are very significant for the reconstruction of the trauma and the deformations created thereafter. Various bone forming and promoting agents are widely studied. Hence, in this study, we aim to evaluate the osteoinduction effect of scaffold impregnated with Simvastatin in wistor rats in an observational study. Material and Methods: We implanted 18 Wistar rats to be equally divided as controls and test groups. Polycaprolactone coated with 20 mg concentration of Simavastatin under sterile condition was used as test and hydroxy appetite as control. Then, we observed the histopathological Heamatoxilin and Eosin and ABH, sections at 4, 12, and 26 weeks. We noted the calcium deposition and bone formation. Results: We observed a significant variation among groups at 4, 12, and 26 weeks in the calcium deposition. While for the bone formation no significant variation were noted among groups at 4 and 12 weeks, however, there was a significant difference noted at 26 weeks. At the end of 12 weeks, mild fibroblast proliferation was seen in the surrounding area. After 26 weeks, ABH sections showed focal area of fibroblast proliferation with mild mononuclear infiltration was noticed; but implant could not be located. Conclusion: We conclude that Simavastatin showed an anabolic effect on bone healing.
In most of the cystic lesions appearing in the oral cavity, proper diagnosis and treatment remains a challenge. As glandular odontogenic cyst (GOC) is a rare type of developmental odontogenic cyst, it was not included in our differential diagnosis. The report of GOC was quite surprising as it was rare and never came in this discussion. A 25-year-old male patient was reported to our center with a chief complaint of painless swelling in the right anterior region of the maxilla. The swelling was oval shaped and diffuse extending from the distal aspect of 11 to the mesial aspect of 14 and superiorly extending into the sulcus. Working diagnosis was a periapical cyst, so conventional treatment of root canal treatment, cyst enucleation, and apicoectomy was done. This article presents a rare case which was primarily misdiagnosed and treated and has been subsequently revealed histopathologically as a rare clinicopathological entity.
Purpose: To localize the impacted maxillary canines in the alveolus using panoramic radiographs. Methods: The present study was a retrospective radiographic chart review of 81 patients with 92 impacted maxillary canines from the Department of oral and maxillofacial surgery, PMS College of Dental Science and Research, Trivandrum. Of the 92 impacted maxillary canines, 57 were impacted buccally and 35 were impacted palatally. The ratio formed between the distance from the crown tips of impacted maxillary canine and ipsilateral central incisors were measured. We used these measurements to predict the position of the tooth and correlate this prediction with the actual approach used during surgery. Results: The ratio of the canines in the buccal group was 1.35± 0.144(range, 1.04 to 1.88). Palatal group has got little higher values with the mean ratio of 1.93± 0.52 (range, 1.29 to 3.22). The ratios were distributed over a scatter plot (Figure 2). The diagnostic test characteristics for the values greater than 1.45, greater than 1.50 and greater than 1.55 were taken. These values were used for constructing a receiver operating curve. There was a better sensitivity and specificity for the values greater than 1.50(sensitivity: 94.29%, specificity: 91.38%). Logistic regression showed that if the ratio is more than 1.50, there is a chance of 19.3 times to get a canine palatally impacted. Conclusion: There is significant difference in the vertical position of buccal and palatal canines in the alveolus. Based on our values we found that palatally impacted canines are restricted more superiorly. Keywords: Localization, impacted maxillary canines, panoramic radiographs, bicondylar line
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