The blood sugar content and the epinephrine discharge after haemor rhage were previously separately studied in non-fastened, non-anaesthetized dogs by two of us;1) 2) the results may be recapitulated as follows: In order to evoke an increase of the blood sugar content a quantity of at least one fourth of the total blood amount must be shed, and the shedding of one third calls forth a significant hyperglycaemia. Double splanchuectomy interferes with the occurrence of hyperglycaemia of a moderate strength, but when a considerable mass of blood is shed, the blood sugar content increases definitely, though only a little, in the bilaterally splanchnectomized dogs. The haemor rhage of one tenth of the total blood quantity acts, on the other hand, to induce invariably a definite acceleration of the epinephrine discharge, and the greater the haemorrhage, the more intensive and longer the acceleration of the epinephrine discharge.Further it is a well substantiated fact that adrenaline exerts an influ ence upon the coagulability of blood.3) The problem of the effect of haemor rhage upon the clotting time of blood was attacked anew by the other of us, 1) Taehi, Tohoku J.

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