No abstract

This systematic review highlights the benefits of bariatric surgery in reducing risk factors for CV disease. There is also evidence for left ventricular hypertrophy regression and improved diastolic function. These observations provide further evidence that bariatric surgery enhances future CV health for obese individuals.

While CLI admission rates have remained constant from 2003 to 2011, rates of surgical revascularization have significantly declined and endovascular revascularization procedures have increased. This has been associated with decreasing rates of in-hospital death and major amputation rates in the United States. Despite multiple adjustments, endovascular revascularization was associated with reduced in-hospital mortality compared to surgical revascularization during 2003 to 2011.

SA does seem to show promise in treatment of HOCM owing to similar mortality rates as well as functional status compared with SM; however, the caveat is increased conduction abnormalities and a higher post-intervention LVOTG. The choice of treatment strategy should be made after a thorough discussion of the procedures with the individual patient.

T ranscatheter aortic valve replacement (TAVR) has revolutionized management of elderly patients with severe aortic stenosis, 1,2 but post-TAVR neurological events remain a concern for patients and physicians. Although occurrence of post-TAVR stroke has fallen from ≈5% in initial trials to 3% in recent reports, reducing this risk is essential for advancing this technology into lower-risk patient cohorts. See Editorial by Dangas and GiustinoUnderstanding the mechanisms of neurological events is critical for developing strategies for reducing their occurrence. Despite several attempts to identify procedure and patient characteristics that may lead to neurological events, the field remains somewhat controversial.3,4 One controversy is the timing of neurological events and its relationship to procedural embolization.5 Different reports have suggested that up to half of the events may be unrelated to procedural embolization, although small numbers of patients and events, Background-Prior studies of stroke and transient ischemic attack (TIA) after transcatheter aortic valve replacement (TAVR) are limited by reporting and follow-up variability. This is a comprehensive analysis of time-related incidence, risk factors, and outcomes of these events. Methods and Results-From 17).Stroke and TIA were associated with lower 1-year survival than expected (TF 47% after stroke versus 82%, and 64% after TIA versus 83%; TA 53% after stroke versus 80%, and 64% after TIA versus 83%). Risk factors for early stroke after TA-TAVR included more postdilatations, pure aortic stenosis without regurgitation, and possibly more pacing runs, earlier date of procedure, and no dual antiplatelet therapy; high pre-TAVR aortic peak gradient was a risk factor for stroke early after TF-TAVR. Conclusions-Risk of stroke or TIA is highest early after TAVR and is associated with increased 1-year mortality.Modifications of TAVR, emboli-prevention devices, and better intraprocedural pharmacological protection may mitigate this risk. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00530894.(Circ Cardiovasc Interv. 2016;9:e002981.