OBJECTIVE:To study the morbidity and the mortality patterns in inborn preterm newborns admitted in NICU at a tertiary care teaching hospital. DESIGN: Retrospective study. The medical records of all the inborn preterm neonates (G. age ≤36W+6 days) who were admitted to the NICU were analyzed by using a pre-set proforma. SETTINGS: Neonatal Intensive Care Unit (NICU), Department of Pediatrics, Adesh Institute of Medical Science & Research Institute (AIMSR) Bathinda, Punjab. The study was carried out over a period of 2 years from January 2012 to December 2014. PARTICIPANTS: 80 preterm neonates who were born in AIMSR and were admitted with some illness to the NICU. OUTCOME: The patterns of the morbidity and the mortality among the preterm neonates who were admitted to the NICU. 'Survival' was defined as the discharge of a live neonate/ infant from the hospital. RESULTS: A total of 80 premature inborn infants were analyzed for the complications they encountered after birth while admitted in NICU. Out of 80 premature babies, 32 (40%) were male and 48 (60%) were female babies. Mean gestational age was and Mean birth weight was. Neonatal hyper-bilirubinemia, HMD/RDS and Neonatal sepsis were the commonest causes of morbidity. Among 80 premature babies 15(18.7%) died. The highest mortality was seen in babies those weighing less than 800 grams (100%). Male mortality is 34.4% and female mortality is 8.3%.

This study was conducted to assess the relationship of vitamin D deficiency (VDD) with various demographic characteristics, laboratory parameters, and predictors of mortality. This prospective observational study was performed at pediatric intensive care unit (PICU) of a tertiary care hospital situated in north India. A total of 125 children admitted in PICU with age from 2 months to 14 years were analyzed. The subjects were classified as Vitamin D deficient (≤20 ng/mL) and nondeficient (>20 ng/mL). The relationship between VDD and predictors of mortality were analyzed using correlation and multivariate analysis. Respiratory system (40%) was most commonly involved. VDD was seen in 72% of the patients. There was statistically significant correlation of VDD with age (p = 0.019), season (p = 0.018), height (p = 0.005), and weight (p = 0.003). On multivariate analysis factors associated with VDD were age (odds ratio [OR] = 1.01, 95% confidence interval [CI] 1.00–1.03, p = 0.006), season (OR = 3.98, 95% CI 1.09–14.50, p = 0.036). VDD was also correlated to bacteriuria (p = 0.033), cardiovascular sequential sepsis-related organ failure assessment score (CV-SOFA score) (p = 0.001), and mechanical ventilation (p = 0.043). On multivariate analysis, factors associated with VDD were bacteriuria (OR = 4.88, 95% CI 1.04–22.89, p = 0.04), mechanical ventilation requirement (OR = 2.95, 95% CI 1.12–7.85, p = 0.029), and CV-SOFA score (OR = 2.33, 95% CI 1.14–4.76, p = 0.021). Median (interquartile range) duration of PICU stay in VDD patients was (3–7) days while in nondeficient patients it was (2–6) days (p = 0.107). VDD was a significant risk factor for the need of mechanical ventilation, bacteriuria, and mortality among patients in our cohort.

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