Acrokeratosis verruciformis of Hopf (AKV) is a rare cutaneous autosomal dominant genodermatosis described by Hopf in 1931. It usually presents at birth or may appear as late as 5 decade of life. It is characterized by multiple hyperkeratotic, verrucous papules/plaques to multiple planar wart like lesions on dorsal aspects of hand and feet. Due to rarity of the case, we present a case of AKV in a 60-year-old male that was diagnosed on histopathology. We the authors have attempted to describe the histological features of AKV with differential diagnosis of these lesions through review of literature.

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Polycystic kidney disease is a rare developmental anomaly inherited as Autosomal dominant or recessive. Autosomal recessive polycystic kidney disease (ARPKD) is an intractable cystic renal disease that results in chronic renal failure. It has a profound effect on growing fetus and result in serious implications if pregnancy is continued in the long run after being detected on sonography. Although prenatal imaging studies and clinical findings are suggestive of ARPKD it can be accurately diagnosed by histopathology if an autopsy is performed in cases of infant death. In this article we here in present the features of ARPKD diagnosed antenatally by USG in a 22 yr female, and was confirmed further by fetal autopsy.