We report a 52-year-old patient with cutaneous angiomas on the trunk in association with angiotropic lymphoma involving the nervous system. The lesional skin showed proliferation of atypical B cells in the capillaries. The diagnosis of angiotropic lymphoma with neurological deficits is often difficult before death. Thus, skin biopsy in this case proved to be diagnostic of the central nervous system disease without the risk of brain biopsy. The diagnosis of angiotropic lymphoma in the future may be achievable by biopsy of coincidental angiomas.

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The additional low dose tacrolimus therapy for steroid-dependent thymectomised MG is effective in improving symptoms as well as allowing the tapering of CSs.

Accommodation power was measured with pattern visual evoked potentials in 12 normal subjects and three patients suffering from psychogenic visual disturbances and accommodation failure. Steady-state visual evoked cortical potentials recorded by increasing a minus-power lens in front of the eye in 1 diopter steps. The regression line was established from the visual evoked cortical potential amplitudes vs accommodation stimulus plot, and the objective accommodation power was determined by extrapolating the line to zero amplitude. The accommodation power measured by visual evoked cortical potentials was larger by approximately 2 diopters than that obtained subjectively by near-point rule in normal subjects. The subjective accommodation power was remarkably low for their age in each patient but the objective power was normal. These results suggest that the decrease of accommodation in these patients was caused by psychogenic mechanisms, and visual evoked cortical potential measurements of accommodation could provide helpful information for diagnosis.

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