Medicinal plants are moving from border to mainstream use with a more number of people seeking treatment and health approaches free from side effects caused by synthetic chemicals. India officially recognizes over 3500 plants for their medicinal value. It is generally estimated that over 6000 plants in India are in use in folk, traditional and herbal medicine. This review article aims to provide a comprehensive review on the phytochemical and various pharmacological aspects of Acalypha indica. This plant widely used in traditional medicinal system of India and many other countries has been reported to possess anti-cancer, anti-diabetic, anti-oxidant, anti-bacterial, antifungal hepatoprotective, anti-inflammatory, and also used to check anti-ulcers and wounds healing. It is known as a rich source of glycosides, flavanoids and tannins. The medicinal properties and therapeutic uses of Acalypha indica and its secondary metabolites investigations prove its importance as a valuable medicinal plant.

Cancer is the name given to a collection of related diseases. In all types of cancer, some of the body’s cells begin to divide without stopping and spread into surrounding tissues. Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Research advances over the past two decades have changed the landscape of breast cancer care. Genetic testing, targeted treatments and more precise surgical techniques have helped boost survival rates in some cases while helping to support breast cancer patients’ quality of life. The herb Acalypha indica which belongs to Euphorbiaceae family has multiple medicinal properties which include anti-fungal, anti-bacterial, anti-oxidant, anti-inflammatory, anti-helmintic, anti-ulcer, anti-venom, anticancerous, and neuro-protective activity. The present study emphasises cytotoxic activity of hexane leaf crude extract of Acalypha indica Linn. On mcf-7cell lines by MTT (3-(4, 5-Dimethylthiazol-2)-2,5- Diphenyltetrazolium Bromide) assay method using Cisplatin as a positive control. Hexane Crude extract of different concentrations (10µg/ml, 25µg/ml, 50µg/ml and 100µg/ml) were treated with cell lines, Out of these concentrations 50µg/ml showed maximum inhibitory effect (IC50 value). Hence the present study is taken up to systematically evaluate the anti-cancer properties of the extracts and also to isolate and characterize the active principles of Acalypha indica.

A b s t r a c tThe herb properties which include anti anti was indica petroleum ether. Fresh leaves of the plant were collected and shade milled to obtain powder. Powder was subjected to soxhlet extraction using solvents and extracts were successively obtained. Phytochemical analysis was conducted following standard methods. Phytochemical analysis showed the presen Saponins, Flavanoids and Amino acids. Leaf extract of methonal have shown the highest anti oxidation capacity than hexane, ethyl acetate and petroleum ether. Anti been performed on microbes like sps.results provide evidence that antimicrobial and antioxid analysis for finding potent medicines for diseases.