This study evaluated the ability of different types of silver diammine fluoride (SDF) to inhibit dentin demineralization using microfocused X-ray computed-tomography (µCT). Dentin specimens were divided into five groups (n=10); no-treatment (control), 3.8% SDF (RC), 38% SDF, 38% SDF with potassium iodide (SDF/KI), and potassium fluoride (KF). The treated-dentin surfaces were subjected to demineralization for 7-days and assessed using µCT to determine mineral loss (ML) values. Specimens were also analyzed with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). The ML values of the SDF and KF groups were significantly lower than those of the RC and SDF/KI groups. EDS detected fluoride ions in the SDF and KF groups but not in the RC and SDF/KI groups. It was concluded that 38% SDF demonstrated a high ability to inhibit dentin demineralization while additional application of KI may diminish the inhibitory effect of SDF. The amount of dentin demineralization with SDF treatments was material dependent.

This study compared the effect of experimental polymer-based desensitizers with NaF and oxalic acid (OA) for preventing root demineralization via observation using micro-CT. Bovine root dentin surfaces were treated with coating materials: no treatment; MS0(+) (MS Coat One ® ); MS3000(+) (MS Coat ® ); MS0(−); MS3000(−); MS7000(+/−); fluoride gel (NaF9000). MS; MS polymer, 0-7000; NaF concentrations, (+/−); OA. The specimens were scanned using micro-CT before and after demineralization (pH4.5, 10 h). Following this, the mean mineral loss (ML) after demineralization was calculated, and the specimens were observed under a scanning electron microscope (SEM). The ML values of MS3000(+), MS7000(−), MS7000(+) and NaF9000 were significantly lower than the other groups (p<0.05). Under an SEM, a membrane structure was observed to have formed on the dentin surface in the presence of the MS, fluoride, and OA. The experimental polymer-based desensitizer with oxalic acid and a high concentration of fluoride is effective for preventing root demineralization.