Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and has a poor prognosis unless treated. The aim of this work was to assess HCC cases after transarterial chemoembolization by subtraction dynamic contrast enhanced MRI to detect its accuracy, sensitivity and specificity in detecting residual tumor and assess the need for further treatment. Methods: 35 patients with 42 HCC lesions underwent transarterial chemoembolization were included in this study. Those patients underwent MRI after 3 months where dynamic MRI and subtraction dynamic MRI were obtained. The interpretation of dynamic MRI and the subtraction dynamic MRI was done by two different readers experienced in hepatic imaging blinded to each other. Patients were classified according to reactivity rate into 2 independent groups: Reactive group (30 patients), Not reactive group (5 patients). Results: Comparative study between D-MRIand DS-MRI assessments revealed; highly significant increase in reactivity rate in DS-MRI in HCC patients during 1 st and 2 nd readings; with highly significant difference (p = 0.0078 respectively). By using ROC-curve analysis, DS-MRI assessment discriminated patients with reactivity from patients without, with perfect accuracy, sensitivity= 100% and specificity= 100% (p < 0.0001). Conclusion: Dynamic MRI is valuable in detecting recurrent lesions however, this value is augmented by the addition of subtraction technique especially in lesions having high signal before administration of contrast medium.
Background: DWI is beneficial in evaluation of soft tissue sarcomas, thus improving the diagnostic accuracy, characterization and response to treatment. Purpose: The aim of this study was to evaluate the benefit of using quantitative diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping in the diagnosis of soft tissue sarcoma, with emphasis on its prognostic value. Patients and Methods: This study included 50 patients with pathologically proven soft tissue sarcoma. The DWI was obtained with 3 b values, including 0, 400, and 800 s/mm². Calculation of the ADC value of the lesion was done by placing the region of interest (ROI) to include the largest area of the lesion. ADC values were compared with the histopathology. Results: The most frequent site was thigh (48.0), followed by shoulder, forearm, arm and foot (8.0% for each). The most frequent pathology was synovial sarcoma (32.0%) followed by spindle cell sarcoma (28.0%) then liposarcoma (12.0%). 80% of lesions showed restricted diffusion. Median ADC value was 0.7 and ranged from 0.5 to 2.4. All patients underwent surgery, 48.0% of patients received chemotherapy and 52.0% received radiotherapy. 56.0% of patients showed recurrence, while 44.0% showed metastasis. Mean follow up duration was 13 months with standard deviation of 5 months. Median ADC value was significantly higher in patients with no recurrence (0.9) compared to those with recurrence (0.7).P value was 0.016. Conclusion: DWI with ADC mapping of soft tissue sarcoma has additive role to anatomic sequences for lesion characterization and grading as well as treatment response.
Breast cancer screening and assessment of symptomatic and newly diagnosed breast cancer patients often encounter axillary adenopathy in diagnostic radiology practise. Axillary adenopathy may be caused by a wide range of disorders. Doctors who are familiar with normal and aberrant nodal morphology and the many causes of adenopathy are more equipped to make an appropriate diagnosis. US is the primary imaging modality for assessing axillary lymph nodes on mammograms, computed tomography (CT), and magnetic resonance imaging. All breast associated axillary masses were studied for their Sonographic and Color Doppler features. Methods: Patients with clinically suspected axillary edoema were enrolled in this investigation, which was conducted in a prospective manner. There was a medical history form completed for each of the participants in this research (Detailed history of the complaint -Results of the clinical examination-Any previous radiological or laboratory examination). The axilla and breast are examined using clinical, ultrasound, and colour Doppler techniques. Further imaging will correlate the results of the ultrasound. Both (Clinical examinations) were used to get the final diagnosis. -MRI. After a biopsy, there is a follow up. Results: Malignant lesions accounted for 35.9% of all related breast lesions, followed by fibroadenosis (25%), and fibrodenoma (9.4%). The most prevalent breast mass was a simple cyst in 3.1 percent of cases, followed by abcess, mastitis, fibrocystic disease, and an accessory breast. Age, marital status, pregnancy and breastfeeding, as well as HTN,DM,SLE, cardiac illness, and bronchial asthma, did not have a significant connection with axillary lesion identified by US, while, HTN,DM,SLE, cardiac disease, and bronchial asthma did. There was a substantial difference in the onset, course, and duration of illness between axillary lesions diagnosed by US. Diagnosis by ultrasound revealed considerable differences in the symptoms of axillary tumours in terms of pain, redness, and heat. US diagnosis of axillary lesions was not significantly different from trauma or discharge. Differences in the location, size, and shape of axillary lesions were found when axillary lesions were analysed by US. While a non-specific lymph node is more likely to be oval or rounded, a suspicious lymph node is more likely to be globular. A considerable discrepancy in the axillary lesions' vascularity and cortical thickness was found between those diagnosed by ultrasound and those by conventional imaging methods based on radiological parameters such as hilum, consistency, and echo pattern. Normal echopattern, solid firmness, normal surrounding parynchyma, and normal cortical thickness were seen in the nonspecific lymph node. Lt and both breasts were found to have soft consistency, form, (smooth, speculated, regular uneven) margins, and substantial ascocation with axillary lesion diagnosis in terms of clinical characteristics. Axillary breast lesions were not related with fibbroglandular lesions in terms of radiologic...
Purpose: to evaluate the accuracy of ultra sound guided tru -cut biopsy in non palbable suspicious breast lesions and correlate with pathological results.Introduction: Tru-cut biopsy may be a exact elective will fine needle desire cytology (FNAC) in the finding for breast lesions for a helter skelter symptomatic exactness Similarly as it supplies sufficient tissue to pathologists to create a right histological appraisal. Currently it is those main favored methodology for the finding about breast lesions former should operation rendering should its low cost, secondary accuracy, negligible complications, safe and short duration of the time system. Additionally it might save a considerable measure about liabilities Also unnecessary surgical methods likewise lessens the affinity of muddled surgical methods Also minimizes tolerant anxiety with considerate lesions. Done patients for threatening lesions, What's more should Hosting symptomatic significance, TCB additionally gives sufficient tissue for the assessment from claiming atomic markers which need amazing restorative esteem.Patients and methods: This prospective, controlled ponder selected 40 female patients with non-palpable breast massenet undergone ultimo heartless guided biopsy (USGB) What's more excisional breast biopsy. Post-operative obsessive examination of the example required been directed to guarantee precision for tru-cut biopsy.Results: Special case patient of the instances required false negative outcome about tru-cut biopsy in examination for postoperative excisional biopsy.Conclusion: Ultimo heartless guided biopsy (USGB) may be vital done finding suspicious non palbable breast massenet that guarantee secondary precision outcomes.
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