A rolling bearing is an essential component of a rotating mechanical transmission system. Its performance and quality directly affects the life and reliability of machinery. Bearings' performance and reliability need high requirements because of a more complex and poor working conditions of bearings. A bearing with high reliability reduces equipment operation accidents, equipment maintenance costs and achieves condition-based maintenance. First in this paper, the development of technology of the main individual physical condition monitoring and fault diagnosis of rolling bearings are introduced, then the fault diagnosis technology of multi-sensors information fusion is introduced, finally the advantages, disadvantages and trends developed in the future of the detection main individual physics technology and multi-sensors information fusion technology are summarized. This paper is expected to provide the necessary basis for the follow-up study of the fault diagnosis of rolling bearings and a foundational knowledge for researchers about rolling bearings.

BackgroundAspirin is widely used for preventing ischaemic events. About 20%–40% of patients have aspirin resistance (ASR), which prevents them from benefiting from aspirin medication. This study aimed to develop and validate a model based on single-nucleotide polymorphism (SNP) to distinguish ASR patients.MethodsWe included patients with spontaneous intracerebral haemorrhage and continuing antiplatelet therapy from a multicentre, prospective cohort study as the derivation cohort. Thromboelastography (inhibition of arachidonic acid channel<50%) was used to identify ASR. Genotyping was performed to identify the ASR-related SNP. Based on the result of the logistic analysis, the aspirin resistance in the Chinese population score (ASR-CN score) was established, and its accuracy was evaluated using the area under the curve (AUC). Patients receiving dual antiplatelet therapy for unruptured intracranial aneurysm embolism were prospectively included in the validation cohort. After embolism, 30-day ischaemic events, including ischaemic stroke, new or more frequent transient ischaemic attack, stent thrombosis and cerebrovascular death, were recorded.ResultsThe derivation cohort included 212 patients (155 male patients and the median age as 59). 87 (41.0%) individuals were identified with ASR. The multivariate logistic analysis demonstrated six SNPs ofGP1BA, TBXA2R, PTGS2andNOS3as risk factors related to ASR. The ASR-CN score integrating these SNPs performed well to discriminate ASR patients from non-ASR patients (AUC as 0.77). Based on the validation cohort of 372 patients receiving antiplatelet therapy after embolism (including 130 ASR patients), the ASR-CN score continued to distinguish ASR patients with good accuracy (AUC as 0.80). Patients with high a ASR-CN score were more likely to suffer from 30-day ischaemic events after embolism (OR, 1.28; 95% CI, 1.10 to 1.50; p=0.002).ConclusionGP1BA, TBXA2R, PTGS2andNOS3were SNPs related to ASR. The ASR-CN score is an effective tool to discriminate ASR patients, which may guide antiplatelet therapy.Clinical trial registrationSurgical Treatments of Antiplatelet Intracerebral Hemorrhage cohort (unique identifier: ChiCTR1900024406,http://www.chictr.org.cn/edit.aspx?pid=40640&htm=4).

Abstract:The thermal instability is one crucial factor leading to low bearing operation performance. This paper presents a novel experiment device for thermal performance investigation of an aircraft rolling bearings. A bidirectional fixing structure was designed to balance the spindle thermal deformation. The hydraulic loading was used and the oil injection manner was adopted in the new device. Experimental test was conducted using the new device and experimental results were compared with the calculation based on the temperature and thermal nodes theory. The comparison demonstrates that the temperature distribution trends between the theoretical and experimental results remained the same; specifically, the error between the theoretical and experimental results was 1.0 % under the condition of 200kg load and 2250 rpm driving speed. Consequently, the analysis result shows that the new device is feasible and reliable to provide precise thermal characteristics for the aircraft rolling bearings.