Background Newly graduated RNs leaving the nursing profession in the early stages of their career have enormous financial and time implications for nursing organizations and affect the quality of nursing care. Methods An electronic search was conducted for English articles to identify research studies published between 2011–2021 using the following database of PubMed, MEDLINE, CINAHL, PsycINFO, and Scopus. Eligible publications were critically reviewed and scored using standardized critical appraisal instruments from the Joanna Briggs Institute. Results Twenty-one studies were analyzed. The main factors affecting newly graduated registered nurses’ intention to leave the nursing profession included demographic factors, supervisor and peer support, challenges in the workplace, cognitive and affective response to work, work environment, gender stereotypes, autonomous motivation, role models, and resilience. Conclusions The factors affecting newly graduated registered nurses’ intention to leave the nursing profession are multifaceted and should receive continuous attention from nurse managers. The results provide a baseline of data for nurse administrators to develop intervention strategies to mitigate newly graduated registered nurses’ turnover intention.

ObjectivesChronic rhinosinusitis (CRS) reduces the health‐related quality of life and subsequently causes a tremendous socio‐economic impact. Although many studies have been conducted, few have identified a relationship between bacteriological characteristics and different phenotypes or endotypes. Therefore, this study aimed to elucidate the recent trends in bacterial cultures from different types of CRS in the Asian population.MethodsThis retrospective case–control study recruited patients diagnosed with CRS who underwent functional endoscopic sinus surgery (FESS) at a tertiary hospital in Taiwan. The patients were classified into those with chronic rhinosinusitis with nasal polyps (CRSwNP)/chronic rhinosinusitis without nasal polyps (CRSsNP), eosinophilic chronic rhinosinusitis (eCRS)/non‐eosinophilic chronic rhinosinusitis (NECRS), and central compartment atopic disease (CCAD)/lateral‐dominant nasal polyp (LDNP) groups. The demographic data and bacteriological characteristics of the groups were analyzed.ResultsWe included 503 patients, identifying no significant difference between CRSwNP and CRSsNP for several common bacteria in CRS. The number of Staphylococcus epidermidis isolates in culture was significantly higher in the NECRS group (50.46% vs. 32.56%, p = 0.0003) than that in the eCRS group. The number of methicillin‐resistant Staphylococcus aureus (MRSA; 8.51% vs. 2.35%, p = 0.0221) positive isolates was significantly higher in the CCAD group than that in the LDNP group.ConclusionsThis was the first study in Asia to analyze the relationship between bacteriological characteristics and CCAD. MRSA is significantly higher in the CCAD group than that in the LDNP group. Recognizing the unique microbiology of CRSwNP, eCRS, and CCAD is crucial when selecting antimicrobial therapy to lessen the socio‐economic impact.Level of EvidenceLevel 3 Laryngoscope, 2023