Recent advances in smart devices have sustained them as a better alternative for the design of human-machine interaction because they are equipped with accelerometer sensor, gyroscope sensor, and an advanced operating system. This paper presents a continuous hand gestures recognition technique that is capable of continuous recognition of hand gestures using threeaxis accelerometer and gyroscope sensors in a smart device. To reduce the influence of unstableness of a hand making the gesture and compress the data, a gesture coding algorithm is developed. An automatic gesture spotting algorithm is developed to detect the start and end points of meaningful gesture segments. Finally, a gesture is recognized by comparing the gesture code with gesture database using dynamic time warping algorithm. In addition, a prototype system is developed to recognize the continuous hand gestures based human-machine interaction. With the smartphone, the user is able to perform the predefined gestures and control smart appliances using the Samsung AllShare protocol.
Given that basal levels of reactive oxygen species (ROS) are higher in cancer cells, there is a growing school of thought that endorses pro-oxidants as potential chemotherapeutic agents. Intriguingly, cerium oxide (CeO 2 ) nanoparticles can manifest either anti-or pro-oxidant activity as a function of differential pH of various subcellular localizations. In an acidic pH environment, for example, in extracellular milieu of cancer cells, CeO 2 would function as a pro-oxidant. Based on this concept, the present study is designed to investigate the pro-oxidant activities of CeO 2 in human colorectal carcinoma cell line (HCT 116). For comparison, we have also studied the effect of ceria nanoparticles on human embryonic kidney (HEK 293) cells. Dose-dependent viability of cancerous as well as normal cells has been assessed by treating them independently with CeO 2 nanoparticles of different concentrations (5−100 μg/mL) in the culture media. The half maximal inhibitory concentration (IC 50 ) of nanoceria for HCT 116 is found to be 50.48 μg/mL while that for the HEK 293 cell line is 92.03 μg/mL. To understand the intricate molecular mechanisms of CeO 2 -induced cellular apoptosis, a series of experiments have been conducted. The apoptosis-inducing ability of nanoceria has been investigated by Annexin V-FITC staining, caspase 3/9 analysis, cytochrome c release, intracellular ROS analysis, and mitochondrial membrane potential analysis using flow cytometry. Experimental data suggest that CeO 2 treatment causes DNA fragmentation through enhanced generation of ROS, which ultimately leads to cellular apoptosis through the p53-dependent mitochondrial signaling pathway.
Extraction of metals (Ni, Co) from chromite overburden of Sukinda mines of Orissa, India, with the culture filtrate of Aspergillus niger was studied. Results showed that the amounts of metals leached varied directly with reaction temperature and period of fermentation. The culture filtrate was analyzed for citric and oxalic acids, and contained only oxalic acid-the concentration of which increased with time. Although this acid played the major role in leaching of metals, other unidentified metabolites present in the culture filtrate influenced the dissolution of the metals significantly. Maximum recovery of metals from raw and roasted ore samples was achieved at 80 °C with the 21-day culture filtrate containing the highest amount of oxalic acid. Under identical experimental conditions, much higher amounts of the metals were leached from roasted ore. Microstructures of the ore particles were studied by scanning electron microscopy and transmission electron microscopy; the bonding behaviors of metal compounds were identified by Fourier transform infrared spectroscopy which showed that the metals were leached after chelation with oxalic acid.
Silicon nitride (Si 3 N 4 ) nanowires have been prepared by carbothermal reduction followed by the nitridation (CTRN) of silica gel containing ultrafine excess carbon obtained by the decomposition of dextrose over the temperature range of 1200-1350• C. This innovative process involves repeated evacuation followed by purging of nitrogen gas so that the interconnected nanopores of the gel are filled with nitrogen gas prior to heat treatment. During heat treatment at higher temperatures, the presence of nitrogen gas in the nanopores of the gel starts the CTRN reaction simultaneously throughout the bulk of the gel, leading to the formation of Si 3 N 4 nanowires. The in situ generated ultrafine carbon obtained by the decomposition of dextrose decreases the partial pressure of oxygen in the system to stabilize the nanowires. The nanowires synthesized by this process are of ∼500 nm diameter and ∼0.2 mm length. The product was characterized by scanning electron microscope (SEM), energy dispersive x-ray analysis (EDX), x-ray diffraction (XRD) and infrared (IR) spectra.
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