Introduction: Asymptomatic bacteriuria in pregnancy (ABU) is poorly understood and neglected in developing countries. It causes certain lethal maternal and fetal consequences if left untreated including low weighted births, premature delivery, full-blown urinary tract infection and pyelonephritis. Objective: Our aim was to explore such factors having bad impact on pregnancy associated with asymptomatic bacteriuria and aware our community about these unspoken perils so that ABU likelihood may be reduced. Prevalence varies country to country. Developing and low economic countries are suffered more than developed so thereby upgrading and providing basic amenities of life the risk factors may be reduced. Materials and Methods: This was a cross sectional study carried out in department of pathology PUMHSW. Sample size was 377, all selected were 18 years and above. All urinary samples were collected in sterile container and labeled and immediately transported to microbiology laboratory. Dipstick test, wet mount microscopy and Gram's staining were done. Blood, MacConkey's agar was inoculated and streaked with inoculi. Data were analyzed using SPSS version 23. Results:  Samples found unlabeled (02) and contaminated (03) were dropped from study. A total of 372 were study samples. The most of patients were Gram negative 65(90.20%) predominantly Enterobacteriocae. When cultured, 72 were found growth positive (mixed plus pure) while 300 were negative. Risk factors were assayed in culture positive patients (ABU). A large number of patients (74%) belonged to lower economic class. Most common age group varied from 26-30 years (43%). Third trimester was the most common found in 37 patients ((49.3%). Gravid (G3 or more) were strong risk factors and were 55(73.3%).  Most of patients were illiterate 65 (90.27%). The past history of UTI was a significant risk 46(63.88%) while anemia was found statistically insignificant 17(23.61). Conclusion: Asymptomatic bacteriuria is frequent in pregnant females and significantly increased when compounded by past history of UTI and low socioeconomic status. Therefore, it is necessary for mothers to be screened for ABU. There is a need of rapid and reliable screening methods so that upcoming disease burden can be reduced.

Objective: The aim of study is the determination of   prevalence of asymptomatic bacteriuria during antenatal period in PUMHSW, with prevalence of antenatal asymptomatic bacteriuria in neighboring countries. Methodology: This study is Cross Sectional-Prospective, and conducted at the Department of Pathology Peoples University of Medical & Health Sciences (PUMHS) for Women Nawabshah (Shaheed Benazir Abad). All the samples (417) were obtained from the pregnant women attending the Outpatient Department of Gynecology and Obstetrics PUMHS Hospital Nawabshah.All mid-stream clean catch collected urine sample in sterile container processed for urine detailed report (physical, chemical and microscopic examination).All the demographic details were entered and analyzed by SPSS 20.More than 8 international as well as national databases were searched  to  the year 2020, consisting of  google, Pub-med, Science direct, Web of Science, Medline. The data obtained were analyzed and their results reported with a random-effects model with confidence level 95%. Result: Out of 417 patients the mean age of the pregnant female was 29.32± 5.74 years.There were females with mean parity of 2.66 ±2.42 and mean gestational age was25.84± 11.80.Age when compared with asymptomatic bacteriuria revealed statistically significant value p value 0.000 with an increased incidence seen among age group of 26-30yrs n=33(44%).  The total prevalence of asymptomatic bacteriuria (ASB) was 83(19.9%).Age when compared with asymptomatic bacteriuria revealed statistically significant value p value 0.000 with an increased incidence seen among age group of 26-30yrs. Conclusion: Asymptomatic bacteriuria during pregnancy is increasingly found in younger age women, with increasing gestational age. Therefore urine cultures during antenatal period should be done to diagnose asymptomatic bacteriuria in order to make preventative planning and control of asymptomatic bacteriuria among pregnant women.

Background: Meningitis happens all the more ordinarily during the main month of life than during some other ensuing period and it is related with high horribleness and mortality. Objective: The objective of this study is to assess the outcomes of meningitis treatment and its associated risk factors among the children. Methodology: A cross-sectional retrospective study was conducted on 400 children, sample size was calculated by using Slovin’s Formula “n=N÷(1+Ne2)” at 0.05 margin of error and by using convenience sampling. Patients who were diagnosed with bacterial meningitis aged from 0 to 18 years were included in the study. Data was collected by well-structured questionnaire. SPSS version 23.0 was used to analyze the data. Multivariate logistic and Bivariate regression analyses was performed to analyze the data. P value ≤0.05 was considered as statistical significant. Results: 262 (65.5%) males were reported and females were 138 (34.5%). Sepsis was found in 24 (6%) patients due to meningitis. Outcomes of the treatment of meningitis patients were found good among 308 (77%) patients. Conclusion: It was concluded that adjustments of starting anti-toxin routine, level of obviousness at hospitalization and season of show to the medical care office from indication beginning altogether affected therapy results of intense bacterial meningitis in youngsters.

Background: Hypertension is a common health issue all over the world; increased Body Mass Index (BMI) is alone one strong risk factor for the HTN. Objective: To assess the relationship between HTN & BMI in patients visited at department of Medicine PMCH Nawabshah. Methodology: This cross sectional study was conducted at PMC Hospital Nawabshah during March 2019 to February 2020. Sample size was 385. This study was conducted after ethical approval of institutional committee and willing male and female subjects with hypertension were included in present study after consent. Age ranges from 15 years and above. Those having other co morbidities like, DM, IHD, stroke and other metabolic and endocrine disorders were excluded from the study. Patients with history of drugs causing weight gain were also excluded. Results: there were total 385 subjects included, 130 were females and 245 were males1:2 ratio of female and male. Mean age of patients was 46.50 sd ± 8.65 years, mean BMI was 26.18 sd ± 4.73, mean systolic HTN was158.35sd ± 30.40 and mean diastolic blood pressure was 95.75 sd ± 12.91 mmHg. Conclusion: There is strong association between hypertension and BMI, as the BMI will increase the risk of HTN will increase.

Objective: The objective of this study is to assess deficiency of Vitamin D among the Tuberculosis Patients at People’s Medical College Hospital (PMCH) Nawabshah, Pakistan. Methodology: This was a case-control study in which 184 new diagnosed tuberculosis patients aged between 30 to 50 years were selected and 200 were taken as control. The study was conducted from June 2020 to May 2021. Well-structured questionnaire was administered to both case and control groups. Body mass index (BMI) was recorded as (kg/m2). Blood samples were collected for the presence of Vitamin D3 levels. Statistical Software for Social Sciences (SPSS) version 23 was used to analyze the data. Results: The mean age and standard deviation (SD) of the patients was 45.11 ± 7.99 years and gender distribution was females 94/184 (51%) and males 90/184 (49%) in patients. There was Vitamin D deficiency in 79/184 (39%) patients. Conclusion: Vitamin D deficiency was common among tuberculosis patients in contrast to control group. The female patients with low Body Mass Index (BMI) (kg/m2) were having the more deficiency of Vitamin D. Vitamin D supplementation has vital role in tuberculosis treatment and prevention.