In contrast to earlier studies that compared CMRI with morphological examination (CA) alone, the present study compared CMRI with CA plus a standard invasive functional assessment (FFR) and demonstrated that CMRI is able to distinguish haemodynamically relevant from non-relevant coronary lesions with a high sensitivity and specificity and may therefore contribute to clinical decision-making.

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The Synergistic Processor Element (SPE) is the first implementation of a new processor architecture designed to accelerate media and streaming workloads. Area and power efficiency are important enablers for multi-core designs that take advantage of parallelism in applications [2]. The architecture reduces area and power by solving scheduling problems such as data fetch and branch prediction in software. SPE provides an isolated execution mode that restricts access to certain resources to validated programs.The focus on efficiency comes at the cost of multi-user operating system support. SPE load and store instructions are performed within a local address space, not in system address space. The local address space is untranslated, unguarded and non-coherent with respect to the system address space and is serviced by the local store (LS). Loads, stores and instruction fetch complete without exception, greatly simplifying the core design. The LS is a fully pipelined, single-ported, 256kb SRAM [3] that supports quadword (16B) or line (128B) access.The SPE is a SIMD processor programmable in high level languages such as C or C++ with intrinsics. Most instructions process 128b operands, divided into four 32b words. The 128b operands are stored in a 128-entry-unified-register file used for integer, floating point and conditional operations. The large register file facilitates deep unrolling to fill execution pipelines. Figure 7.4.1 shows how the SPE is organized as well as the key bandwidths (per cycle) between units.Instructions are fetched from the LS in 32 4B groups. Fetch groups are aligned to 64B boundaries to improve the effective instruction fetch bandwidth. 3.5 fetched lines are stored in the instruction line buffer (ILB) [1]. One-half line holds instructions while they are sequenced into the issue logic; as another line holds the single entry software managed branch target buffer (SMBTB) and two lines are used for inline prefetching. Efficient software manages branches in three ways: it replaces branches with bit-wise select instructions; it arranges for the common case to be inline; it inserts branch hint instructions to identify branches and load the probable targets into the SMBTB.The SPE can issue up to two instructions per cycle to seven execution units organized in two execution pipelines. Instructions are issued in program order. Instruction fetch sends double word address-aligned instruction pairs to the issue logic. Instruction pairs are issued if the first instruction (from an even address) is routed to an even pipe unit and the second instruction to an odd pipe unit. Loads and stores wait in the issue stage for an available LS cycle. Issue control and distribution require three cycles. Figure 7.4.5 details the eight execution units. Unit to pipeline assignment maximizes performance given the rigid issue rules. Simple fixed point [4], floating point [5] and load results are bypassed directly from the unit output to input operands reducing result latency. Other results are sent to the forward macro whe...

The IBM POWER6e microprocessor core includes two accelerators for increasing performance of specific workloads. The vector multimedia extension (VMX) provides a vector acceleration of graphic and scientific workloads. It provides single instructions that work on multiple data elements. The instructions separate a 128-bit vector into different components that are operated on concurrently. The decimal floating-point unit (DFU) provides acceleration of commercial workloads, more specifically, financial transactions. It provides a new number system that performs implicit rounding to decimal radix points, a feature essential to monetary transactions. The IBM POWERe processor instruction set is substantially expanded with the addition of these two accelerators. The VMX architecture contains 176 instructions, while the DFU architecture adds 54 instructions to the base architecture. The IEEE 754R Binary Floating-Point Arithmetic Standard defines decimal floating-point formats, and the POWER6 processor-on which a substantial amount of area has been devoted to increasing performance of both scientific and commercial workloads-is the first commercial hardware implementation of this format.

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