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Membrane lipid peroxidation and DNA, protein damage is mediated by free radicals, which form the basis of chronic pathological complications.AgNPs are an important class of nanomaterials for a wide range of biomedical applications. The present study endeavors in vitro antioxidant and anti-inflammatory activity of green synthesized silver nanoparticles (AgNPs) using medicinal plant extract from Caesalpinia bonducella seeds. Total flavonoid and phenolic contents were determined. The antioxidant potential of capped AgNPs was assessed using DPPH assay, Phosphomolybdenum assay, FRAP assay, metal chelating, hydrogen peroxide, and hydroxyl radical scavenging methods. In vitro anti-inflammatory assay of CB seed, AgNPs were performed against the standard drug. CB seed AgNPs possessed high flavonoid and phenol compared to aqueous CB seed extract. The antioxidant methods confirmed that the silver nanoparticles have more antioxidant activity as compared to vitamin C. The synthesized silver nanoparticles exhibited potential anti-inflammatory activity with the IC50 71.3µg/ml. Hence, this work clearly demonstrated that the coated AgNPs with CB seeds act as a potent free radical scavenger and could be considered as a potential source for anti-inflammatory drugs.

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The present investigation was undertaken to find the seasonal incidence of major insect pests of brinjal during kharif 2019 at the Research farm, College of Agriculture, Tikamgarh (M.P.). The results revealed that the incidence of sucking insect pests viz., whitefly (Bemisia tabaci) started from last week of September (39th standard week) with a population of 4.89/ 3 leaves and reached to a peak level during the second week of October (41st standard week) with a population of 8.96/ 3 leaves whereas jassid (Amrasca biguttula biguttula) started from last week of September (39th standard week) with a population of 0.80/ 3 leaves and reached to a peak level during the second week of October (41st standard week) with a population of 1.29/ 3 leaves. The incidence of shoot and fruit borer started from second week of October (41st standard week) with 4.0% shoot infestation and reached its peak during the second week of November (46th standard week) with 20.0% shoot infestation. Highest fruit infestation of 50% was recorded during the first week of December (49th standard week). Correlation studies showed that among the various abiotic factors, maximum (r= 0.73) and minimum temperature (r= 0.79) exhibited highly significant positive correlation and morning relative humidity exhibited significant negative correlation (r= -0.56) with whitefly population. In case of jassid population, maximum temperature exhibited significant positive correlation (r= 0.59) and minimum temperature exhibited highly significant positive correlation (r= 0.79) with jassid population. The incidence of shoot and fruit borer showed significant negative correlation with minimum temperature and rainfall (r = -0.77, -0.56, respectively).

Extracellular polymeric substances are present abundantly in the surroundings which are produced by different types of microorganisms like bacteria, fungi, algae are also produced by different varieties of plant species. Exopolysaccharides (EPS) are high-molecular-weight polysaccharides secreted by microorganisms into the surrounding environment. These polysaccharides have tremendous application in pharmaceutical industries. For the past two decades, exopolysaccharides of fungus have been known to have high-value biomacromolecules. In most of the studies, sugar compositions of fungus Exopolysaccharaide and variation in molecular weight depend upon culture medium composition and different physical conditions that take place during the process of fermentation. In this current study, the selection of nutrients for the EPS production from Curvularia lunata under submerged batch-culture conditions was made using the Plackett - Burman design matrix method. Subsequently, the optimal condition was determined using Response Surface Methodology (RSM). Thus, produced EPS was characterized by GC-MS and thermogravimetric analysis. It was found to have glucose and mannitol and also showed good thermal stability. EPS was subjected to DPPH assay for analyzing antioxidant activity. Free radical scavenging activity was observed by subjecting the sample to the ABTS method and anticancer activities were tested against HeLa cells. EPS was found to be having a good antioxidant activity, Free radical scavenging activity and showed effective anticancer activity against HeLa cells.