Background: Escherichia coli (E. coli) is a rod-shaped gram-negative bacterium included in Multi Drug Resistant (MDR) bacteria. There are several strategies in place to prevent and treat E. coli bacterial infections to reduce some the incidences of MDR. One of them is the development of a protein-based vaccine. Pili is one of virulence factors in E. coli surface proteins that can mediate attachments of bacteria to host cells (adhesin or hemagglutinin) and can be used as protein-based vaccine candidates. Objective: This study aims to determine characterization of pili protein with molecular mass of 85 kDa Escherichia coli bacteria as an adhesin and a hemagglutinin. Methods: This study is a true experimental laboratories and a descriptive study to determine roles of pili protein with molecular mass of 85 kDa as an adhesin and a hemagglutinin. Samples used in this study were a stock of E. coli in the Microbiology Laboratory Faculty of Medicine, Universitas Negeri Jember (UNEJ). A hemagglutination test in this study used mouse erythrocytes while an adhesion test used mouse enterocytes. Isolation and purification of E. coli pili protein, isolation of mouse erythrocytes, isolation of mouse enterocytes, the hemagglutination test and the adhesion test were methods in this study. A data analysis with a correlation-regression was used to determine relationships between the adhesion index and titer pili 85 kDa with a limit of significance, 0.05 (p <0.05). Results: The hemagglutination test showed no ability of agglutination with the formation of red aggregate points starting from the first dilution. An analysis with Pearson correlation indicated a relationship between titer pili 85 kDa E. coli and adhesion index (p = 0.009; R = -0.921). Conclusion: Pili protein 85 kDa E. coli plays a role as an adhesin protein and do not have a role as a hemagglutinin protein. Latar Belakang: Escherichia coli (E. coli) merupakan bakteri Gram negatif yang termasuk dalam bakteriMulti Drug Resistant (MDR). Saat ini ada beberapa strategi dilakukan untuk mencegah dan mengobati infeksi bakteri E. coli sehingga mengurangi angka terjadinya MDR. Salah satunya dengan pengembangan vaksin berbasis protein. Pili merupakan salah satu faktor virulensi pada protein permukaan E. coli yang dapat memperantarai perlekatan bakteri dengan sel inang (adhesin atau hemaglutinin) dan dapat dijadikan kandidat vaksin berbasis protein. Tujuan: Penelitian ini bertujuan untuk mengetahui peran pili 85 kDa E. coli sebagai protein adhesin dan hemaglutinin.
Konvergensi pertumbuhan ekonomi di Jawa Timur memiliki ketimpangan antar kabupaten/kota yang tinggi. Penelitian ini bertujuan untuk menganalisis konvergensi dan faktor-faktor yang mempengaruhi dijawa timur pasca terjadinya krisis global 2008/2009. Data yang digunakan data sekunder yang bersumber dari Badan Pusat Statistik. Analisis yang digunakan dalam penelitian ini adalah analisis least squares. Berdasarkan hasil analisis konvergensi ditunjukkan bahwa pada tahun 2008 pasca krisis global terjadi konvergensi sigma dikabupaten/kota dijawa timur. Namun terjadi konvergensi beta absolut dikabupaten/kota dijawa timur dimana terdapat pengaruh antara PDRB tahun sebelumnya dengan PDRB tahun sesudahnya. Terjadi konvergensi beta kondisional dimana variabel IPM berpengaruh positif signifikan, jumlah pendudukberpengaruh negatif signifikan, dan tenaga kerja berpengaruh positif signifikan terhadap pertumbuhan ekonomi .
Reduktan herbisida dapat menjadi upaya untuk mengurangi penggunaan dosis herbisida tanpa mempengaruhi keefektifannya. Penelitian ini bertujuan untuk mengetahui keefektifan dari penggunaan reduktan herbisida dalam mengendalikan gulma serta pengaruhnya terhadap tanaman padi varietas Inpari 32. Penelitian ini menggunakan Rancangan Acak Kelompok dua faktor dengan tiga ulangan. Faktor pertama yaitu jenis bahan aktif herbisida (M) dan faktor kedua yaitu dosis reduktan herbisida (N). Hasil penelitian menunjukkan bahwa perlakuan dengan reduktan herbisida efektif mampu menekan pertumbuhan gulma golongan daun lebar dan teki. Semua petak perlakuan menujukkan potensi newgrowth (pertumbuhan gulma baru) serta regrowth (pertumbuhan gulma kembali) pada semua golongan gulma. Bahan aktif M2 (Etoksisulfuron 20 g/l dan fenoksaprop – p – etil 69 g/l) menunjukkan gejala fitotoksisitas dengan skor 1,11 pada waktu pengamatan satu minggu setelah aplikasi. Semua herbisida perlakuan menunjukkan pengaruh berbeda tidak nyata terhadap parameter pengamatan tanaman padi (tinggi tanaman, jumlah anakan total, laju pertumbuhan tanaman, jumlah anakan produktif, bobot Gabah Kering Panen serta berat 1000 butir padi). Penggunaan reduktan menunjukkan tingkat efisiensi 18 - 51% dari segi biaya dibandingkan perlakuan tanpa reduktan.
This study aims to determine the management of BUMDes Mandiri and the success factors for the performance of BUMDes Mandiri in Suci Village, Panti District, Jember Regency. The research method used is descriptive qualitative. The type of data needed is primary data with data collection techniques by observation, interviews with BUMDes Mandiri administrators and documentation. The results showed that the main business activity of BUMDes Mandiri was selling household goods with cash and credit payments with a marketing strategy that was by utilizing the existing village apparatus and routine recitation activities for mothers. There are still no competitors in the Suci village, making it easier for BUMDes Mandiri to carry out their business activities. Independent BUMDes employees still need assistance from the sub-district in completing BUMDes financial reports. BUMDes Mandiri in 2021 will only compile a bank subsidiary ledger, general cash book, and cash subsidiary ledger
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