This article devises a new adaptive fixed-time tracking control strategy for interconnected nonlinear systems containing partially unmeasurable states and time-varying output constraints. Radial basis function neural networks, as function approximators, are utilized to model the unknown functions, and the partially unmeasurable states of the systems are estimated by a reduced-order observer. By constructing a transferred function, system outputs are directly constrained in a time-varying constraint bound. Meanwhile, the first-order sliding mode differentiators are utilized to reduce the computational burden caused by the repeated differentiations of virtual controllers. Under the Lyapunov function and the fixed-time theory, the decentralized adaptive fixed-time controllers are constructed. It is proved that the closed-loop systems are fixed-time stable and the output signals are restricted in the bounded compact set. Finally, two simulation examples demonstrate the validity of the proposed control scheme.
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