SummaryThis paper addresses the event‐triggered stabilization control for multi‐input and multi‐output (MIMO) nonlinear systems. To handle the “explosion of complexity”, the dynamic surface control (DSC) technology is introduced to the proposed control scheme. In addition, the event‐driven idea is adopted to mitigate the data transmission pressure in sensor‐to‐controller and controller‐to‐actuator channels. Considering that the non‐derivable virtual controllers are commonly constructed in the event‐triggered control schemes aiming at saving dual‐channel resources, in this paper, a hybrid event‐triggering mechanism with multiple event detectors is developed to obtain differentiable virtual control signals, thereby providing a suitable application environment for the DSC technology. Meanwhile, an output‐based adaptive threshold is designed to obtain more communication benefits compared with the fixed threshold strategy. Finally, all signals in the closed‐loop system are ensured to be bounded under a standard Lyapunov stability analysis framework, and the effectiveness of the proposed control scheme is validated by a simulation example.