Objective: To compare the treatment outcome of Silodosin alone and Silodosin plusTadalafil as a medical expulsive therapy (MET) of lower ureteric stone in south-westernpart of Bangladesh. Methodology: The study was conducted in a tertiary hospital in Khulna, over a periodof 12 months (January 2019 to December 2019). Out of 108 patients, 100 meet theinclusion criteria who were purposively assigned into 2 groups. 48 patients included inSilodosin alone group and 52 in Silodosin plus Tadalafil group. Result: There was a significant higher stone expulsion rate in Silodosin plus Tadalafilthan Silodosin alone which was 88.46% vs75% respectively (P value 0.02). The meanstone expulsion time of Silodosin alone was14.33 (±3.1) days and Silodosin plus Tadalafilwas 11.48(±2.3) days (P value 0.001). The episodes of pain in Silodosin alone were0.7(±0.06) and 0.6(±0.2) in Silodosin plus Tadalafil group that was statisticallysignificant. Conclusion: The present study concludes that Silodosin plus tadalafil combinationtherapy significantly increases ureteric stone expulsion rate and decreases the expulsiontime and pain episodes than treatment with silodosin alone. Bangladesh Journal of Urology, Vol. 23, No. 1, January 2020 p.67-71

More than 90% of malignant renal tumors encountered in children are Nephroblastoma. Renal Cell Carcinoma is extremely rare in children but in children older than 5 years with renal masses it is very important to suspect diagnosis. We present a 6 years old child primarily presented with abdominal mass and haematuria. The mass was described by ultrasonography & computer tomography as Wilms’ Tumour which is commonest before 5 years of age with peak age of presentation is 3 years of life. Surgery is the best treatment and prognosis is favorable when tumour is localized and completely eradicated. In our case no adjuvant therapy was given nephrectomy Bangladesh Journal of Urology, Vol. 20, No. 2, July 2017 p.102-104

Not Available Bangladesh Journal of Urology, Vol. 20, No. 2, July 2017 p.105-108

Introduction: Radical Cystectomy (RC) is an effective surgical procedure for muscle invasive bladder cancer ( MIBC). 5 years disease free survival after RCs are PT2 - 81%, PT3a – 68%, PT3b – 47%, PT4a – 44% respectively, Stein et al, 2001[1]. In this study early surgical & oncological outcome have been assessed. Patients & methods: A total of 24(N) patients underwent radical cystectomy with urinary diversion between December 2013 to June 2016. Age ranges from 41-69 years. Indications were T2HG for twenty cases and T1HG for four cases. Among the T1 tumours, one had early recurrence, one had numerous tumours and two had multiple tumours with concomitant CIS. Urinary diversion methods were: Orthotopic Ileal neobladder-1, Ileal conduit-20, Cuteneous Ureterostomy -3 (2 due to unhealthy mesentry with gut, 1 single kidney with poor general condition), For uretero-Ileal anaestomosis we used Bricker method in all cases. Result: Mean OR time was 3:45 hours, blood loss average 350 ml, hospital stay after operation 9 days, enlarged pelvic lymph nodes were found in two cases. In follow up we found,stomal stenosis of cutaneous ureterostomy in 1 out of 3 cases, Ileal conduit prolapse with para-stomal hernia in 1 out of 20 cases, stenosis at uretero-Ileal anastomosis in 1 pt. .Distant recurrence occurred in two cases, one in Lt. Supraclavicular LN and another in sacrum near SI joint. No local recurrence was found in any case. Conclusion: Our experience on RC and all the three types of UD are safe and effective for patient and encouraging for us. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.62-65

Objective: The aim was to describe the clinicopathological presentation of prostate cancer and the treatment modality in patients seen in Uro-oncology department of National Institute of Cancer Research & Hospital (NICRH), Bangladesh. Methods: Data were collected prospectively from all patients with diagnosed prostate cancer and managed in Uro-oncology department of NICRH from January 2016 to December 2017. Patient’s age, clinical presentation, prostate specific antigen(PSA) level, mode of diagnosis, Gleason sum score, stage of the disease at presentation and modality of treatment were recorded and analyzed. Results: There were 407 cases of histologically proven prostate cancer. Mean patient age was 69 years. About 87% presented as diagnosed prostate cancer. Twenty one(5%) patient presented with features of metastasis with unknown primary , we confirmed after prostate biopsy. About 77% of patients had a serum PSA above 20 ng/ml. Gleason sum score was 8 or more in 46% of patients. Metastases were found at the time of presentation in 85% of patients. Ten (2.5%) patients underwent radical radiotherapy, while two patients had radical prostatectomy. Most (68%) of the 347 patients who required androgen deprivation therapy had surgical orchiectomy. Conclusion: Bangladesh appear to be having a low incidence of prostate cancer, but a larger proportion of advanced and high grade cancers in comparison to the UK and USA. Although genetic differences may exist, a dietary or an environmental factor is more likely to be the cause for these changes. The protective effect of this factor appears to wane as South Asians emigrate and live in UK and USA. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p 56-61