Introduction After initial studies suggested that pregnant women were not at a higher risk of complications due to COVID‐19 infection. Recent investigations from Sweden and the US have indicated that pregnant and postpartum women are at increased risk of severe complications associated with COVID‐19. This study aims to find out the prevalence of maternal mortality and the clinical course of maternal mortality cases due to COVID-19 pneumonia. Methodology A cross-sectional study was conducted from May 1st, 2020, to April 30th, 2021, at Postgraduate Institute and YCM Hospital Pimpri Pune (Maharashtra), a dedicated COVID hospital during COVID pandemic. During study period, all pregnant women who were diagnosed to have COVID-19 infection by RT PCR/Rapid Antigen Test were admitted and were enrolled for the study. Aim To audit the maternal mortality due to COVID-19 infection. Primary To estimate the prevalence of maternal mortality due to COVID-19 infection in obstetric patients. Secondary To systematically study and analyze the clinical course of infection in mothers who had mortality due to COVID-19 pneumonia. Data collected in standard format regarding Demography, clinical presentation, need for ICU/HDU, CXR findings, laboratory parameters and cases with maternal mortality were studied in detail to fulfill the study objectives. Results Among 871 COVID-19 cases diagnosed during pregnancy, nine patients had maternal mortality due to covid pneumonia. There was no obvious obstetric cause for mortality in these cases. The prevalence of maternal mortality was 0.01 (1.03%). Cases with maternal mortality were mostly in 3rd Trimester (5 of 9 cases) and presented with moderate to severe illness with breathlessness and myalgia in all 9 cases, cough and fever in 7 out of 9 cases, Tachypneoa was noted in all patients. Saturation below 90 in 6 cases and below 94 in 3 cases. Chest X-ray showed bilateral lung affection in all 9 cases. Leukocytosis with raised N:L ratio was predominantly seen, thrombocytopenia noted in 5 cases and elevated levels of acute phase reactants and inflammatory markers such as CRP, S. ferritin, ESR, LDH, D-dimer and S. fibrinogen was observed. None of the study participants received vaccine for COVID-19. Conclusions COVID-19 pneumonia is an additional toll for maternal mortality. Obstetric patients in 2nd and 3rd trimester having COVID-19 infection with late presentation to hospital, moderate to severe disease (RR > 30 min), with raised inflammatory markers (N:L ratio, CRP, Ferritin, d-Dimer, etc.) at presentation, having bilateral lung affection are at risk of poor maternal outcome.
COVID 19 pandemic is one of the biggest challenge to health system of developing as well as developed countries. Because of the novelty of the virus, limited data were available regarding perinatal outcome. The objective of this study is to find out the perinatal outcome in COVID-19 infected mothers who delivered during COVID Pandemic. Methodology A cross sectional study was carried out at PCMC’S Post-Graduate Institute and YCM Hospital Pune (Maharashtra) from 1 May 2020 to 31 October 2021 which was a dedicated COVID hospital during COVID pandemic. A total of 362 maternity patients (including 5 twin pregnancies) having COVID 19 infection who gave birth to 367 Newborns were studied. Maternal COVID -19 infection was diagnosed either by RTPCR test or Rapid Antigen test. Demographic variables, maternal symptoms, labour and neonatal outcome were recorded. RT PCR of neonates at birth was performed. Data was analyzed statistically by using Epi Info Software. Aim To analyze the perinatal outcome among COVID-19 infected mothers who delivered during Covid pandemic. Objectives Study was conducted with the primary objective to analyze the labour outcome, maternal symptoms and secondarily to study maternal demographic profile and to compare disease severity during 1 st and 2 nd wave of COVID and to detect possibility of vertical transmission of COVID-19 in neonates of covid positive mothers. Results 74.2% patients from young reproductive age (21–30 years age) were affected. All socioeconomic classes were affected. 61% patients were multigravida. Normal BMI was noted in 49.8%. 28.2% deliveries were preterm. Caesarean section rate was 50.5%. Following obstetric high risk factors were noted—anaemia in 34.2% followed by previous LSCS in 26.2% cases and preeclampsia in 18.7% Overall 54.6% patients were asymptomatic while 45.4% were symptomatic. Symptomatology between 1 st and 2 nd wave showed statistical significance (p value < .05%) for mild, moderate and severe symptoms. Myalgia, cough, fever and fatigue were common presenting symptoms. 14% patients required ICU/HDU care. HDU/ICU requirement showed statistical significance (p value < .05) between 1 st and 2 nd wave. Overall maternal mortality was 1.1% (4 maternal deaths in 2 nd wave) with no mortality in 1 st wave. 96.4% were live births. Birth weight was more than 2.5 kg in 62% cases and 21.3% cases required NICU. Vertical transmission of COVID was seen in 1.1% cases. Conclusion Pregnant patients with moderate and severe disease are at higher risk of perinatal complications. ICU/HDU management with multidisciplinary management may reduce morbidity and mortality. Neonatal af...
Stress urinary incontinence is defined as the involuntary loss of urine through the intact urethra caused by a sudden increase in intraabdominal pressure on coughing, walking and in some cases during turning in bed. It is the most common type of urinary incontinence in woman and when it is of sufficient quantity causes a great embarrassment which was frequently underreported UI impairs quality of life, affecting the older person's emotional well-being, social function, and general health. Incontinent persons often manage to maintain their activities, but with an increased burden of coping, embarrassment, and poor self-perception. Caregiver burden is higher with incontinent older persons. This was a hospital based retrospective study in the department of Gynecolog at kem hospital mumbai India. Total duration of study from enrollment to completion was 2 years. Each patient was followed for 6 month In the present study the patient presenting to gynecology OPD of k. e. m. hospital with complaint of urinary incontinence were studied. A total 50. patient were included in following study. Working definition was used for classification. History was documented including Age, occupation, severity, duration and frequency of SUI, other menstrual history, urinary symptoms, detail obstetric history, parity, gynecological procedure, pelvic floor trauma, previous urinary tract infection, previous surgeries. trauma in childhood, any spinal surgery, or drugs. A focused physical examination was performed. Lastly stress incontinence was clinically confirmed by “ Bonneys test “. Anal sphincter tone ad sensation at S dermatomes are checked to rule out any neurological lesion. The data were analyzed using appropriate statistical tool. A total no patient enrolled was 50 during the study period. Majority of the patients fall in the range of 30-50 year of age. Most of the patient having duration of symptoms less than 2 year with more common SUI in multiparty patient, about 60% of patient were having SUI without any previous surgery, 62% of SUI was associated with prolapsed with cystorectocele. In I ntraoperative complication only one patient having bladder perforation in TVT procedure. In post operative complication urinary retention was found 30% in kellys placation, 20% in stameys, 20% in TVT, 00% in TOT. However only kellys plication has more recurrence of SUI in about 33%, 12.5% of recurrence in TVT and 8.3% in TOT of patient. As in stameys the number of follow up patient was only two and none of them had recurrence of sui. This study is concluded that, since the symptoms of SUI are not life threatening and most of the female are less health conscious the medical help is not sought for longer duration. In the study TOT procedure was found superior with respect long term failure rate and also intra and post operative complication
Submission of an original paper with copyright agreement and authorship responsibility.I (corresponding author) certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.Thanking you.
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