A series of novel chitosan-zeolite-sulfathiazole nanocomposite (CSFZ) films were prepared by using solvent casting method for wound healing application. The physicochemical properties namely thickness, folding endurance, water absorption capacity, and water vapour transmission rate (WVTR) of the films were studied. Fourier transform infrared spectroscopy (FTIR) was employed to ascertain the interaction between negatively charged zeolite and positively charged chitosan. The surface morphology of the prepared composite films was also studied by scanning electron microscopy (SEM). Due to strong hydrophilic nature of zeolite, it great lyenhances the water absorption capacities of the prepared nanocomposite films. In addition, the presence of zeolite in the said films also increases the mechanical strength. The above analysis suggested that the CSFZ films could be used as potential candidates for wound healing application.

Psoriatic arthritis is an inflammatory joint disease associated with psoriasis vulgaris, with routinely negative rheumatoid factors and the absence of rheumatoid nodules. This is an immune-mediated disease, according to generally accepted definition of Wright and Moll from 1973. American Association against Rheumatism classified psoriatic arthritis as an independent disease in 1964. Psoriatic arthritis is a single disease with a varied clinical picture. It belongs to the group of seronegative spondyloarthropathies with which there are general clinical features. It is believed that similar mechanisms determine the onset of psoriasis and psoriatic arthritis. The clinical picture includes various clinical forms that damage the peripheral and sacroiliac joints, spine, internal organs. The treatment of psoriatic arthritis is directed simultaneously to the influence of skin and joint changes. Purpose: Our study aims to summarize our long-standing experience in the treatment of psoriatic arthritis with heliotherapy. Subject of observation: Monitoring includes 132 patients with moderate and severe form of psoriasis treated at the sanatorium in town of Pomorie for 5 years in the period 2001-2006. Results and discussion: 132 patients with psoriasis with no effect on the local therapy and have proven psoriatic arthritis were selected. In our climatic conditions, heliotherapy is appointed during the warm half-year. Sun treatment was conducted under the conditions of a healing beach, which had shielding, radiation-protective devices. In patients with erythema - pigment and pigment type skin reactivity begins with 1-2 bioadoses reached to 8-10 biodoses, carried out in the area of overcomfort. Conclusion: The studies demonstrated that heliotherapy combined with medications significantly improves the prognosis of patients with this disease. The ultimate success would mean overcoming the frequent depression conditions, better survival and social comfort for patients with psoriatic arthritis.

Childhood obesity is becoming a more important medical and social problem worldwide. The number of overweight children is increasing, and it is becoming more and more difficult to treat, and its role as a risk factor for the development of many diseases at a later age is very high. Obesity in children is predominantly hyperplastic - due to an increased number of fat cells. This explains unsuccessful treatment and the danger to maintain throughout life, because hipirplaziyata of fat cells is irreversible process. The main causes of overweight are: a positive energy balance and a and a disorder of lipid metabolism associated with increased liposynthesis and decreased lipolysis. Children with obesity are characterized by increased appetite, increased thirst, easy tiredness, decreased physical activity and neurotic changes. Parents do not have adequate judgment about the risk of overweight. The problem is that 40% of children aged 6 to 12, who are perceived as normal in weight, are actually overweight and even obese. A very small percentage of parents are worried about this fact. The aim of the study is to establish the percentage of overweight and obese children aged 10-11 years in several Burgas schools. Methodology of the study: measurement of height, weight, body mass index, percentage of fat and muscle tissue. Results and Discussion: The results we have found show a very high percentage of overweight in girls at the age of 11 – about 50%. The boys of the same age overweight was 8.3%. A high percentage of body fat is 37.5% at 11 years old girls, and very high in 12.5%. In boys of the same age we found respectively 16.7% and 8.3%. Conclusion: Screening showed extremely worrying results and proved that overweight in adolescents is becoming a serious problem. The treatment of obesity in children requires a complex approach where active participation takes students who have to be very motivated, as well as their parents and relatives.