The aim of this study was to investigate the effects of oral carbohydrate solution (CHO) on perioperative discomfort, biochemistry, hemodynamics, and patient satisfaction in elective surgery patients under general anesthesia. Sixty cases in ASA I-II group who were planned to have operation under general anesthesia were included in the study. The cases were randomly divided into two groups having 30 subjects in each. The patients in the study group were given CHO in the evening prior to the surgery and 2-3 hr before the anesthesia while routine fasting was applied in the control group. In the study group; 2-3 hr before the surgery; malaise, thirst, hunger, and weakness; just before the surgery malaise, thirst, hunger, and fatigue; 2 hr after the operation thirst, hunger, weakness, and concentration difficulty; 24 hr after the operation malaise and weakness were found significantly lower. Fasting blood glucose (FBG) level was found to be higher in the control group at the 90th min of the operation. Gastric volumes were higher in the control group; gastric pH values were found significantly higher in the study group. The level of anxiety and depression risk rate were found lower in the study group. In conclusion, preoperative CHO reduces perioperative discomfort and improves perioperative well being when compared to overnight fasting.
Giriş
Son yıllarda yayınlanan makaleler incelendiğinde, anestezistlerin preoperatif muayene sırasında her hastayı obstrüktif uyku apnesi (OUA) olasılığı açısından değerlendirmesinin gerekli olduğu anlaşılmaktadır. Bu gereklilik başlıca iki nedene dayanır; ilki, OUA hastalarının %80-90'ının tanı konmamış durumda olmalarıdır (1). İkinci neden ise, Amerikan Anestezistler Birliği'nin (ASA) 2006'da yayımladığı bir kılavuzla, cerrahi hastalara preoperatif dönemde OUA açısından tarama yapılmasını önermiş olmasıdır (2). Preoperatif dönemde kullanılacak uygun bir tarama ile OUA olasılığı yüksek olan hastalar belirlenip, anestezistlerin peroperatif dönemde karşı karşıya kalabilecekleri riskler en aza indirilebilir.Temel özellikleri uykuda solunumun bozulması, horlama ve gün içinde aşırı uyku hali olan OUA, erişkin popülasyonda kadınlarda %2, erkeklerde %4 oranında görülmektedir (3). OUA'nın cerrahi hastalardaki görülme sıklığına dair rakamlar değişkenlik gösterse de, bariatrik cerrahi gibi bazı özel hasta gruplarında çok yüksek oranlarda (%78) izlendiği bildirilmektedir (4-8). Peroperatif komplikasyonlar ile OUA şiddeti arasında doğrudan bir ilişki olduğu bilindiği için, hangi nedenle cerrahi geçirecek olursa olsun OUA hastalarına önceden tanı konularak gereken önlemlerin alınması büyük önem taşımaktadır (2). Bu hastalarda anestezi indüksiyonu sırasında havayolu sağlanmasında zorlukla karşılaşılabilir (9). Ekstübasyondan hemen sonra solunum yolu obstrüksiyonu görülebileceği gibi, postoperatif dönemde verilen
Methods:In 110 adult patients who were admitted to the Sleep Clinic for polysomnography with an initial diagnosis of obstructive sleep apnoea, the STOP-Bang questionnaire was used to calculate the sensitivity, specificity, negative predictive value, positive predictive value and likelihood ratios.
Results:In the study, no significant difference was obtained between two sexes for the presence of high risk of obstructive sleep apnoea (p>0.05). When apnoea-hypopnoea index (AHI) ≤5 patients and AHI >5 patients were compared, no significant differences were found in the values of age, sex and body mass index (p>0.05). Mean AHI value was 1.4 in AHI ≤5 patients, while it was 33.8 in AHI >5 patients (p<0.05). Although both STOP and STOP-Bang screening tests have a high sensitivity (>90%) in various severities of OSA (AHI >5, AHI >15 and AHI >30), their specificities were found to be low. As the severity of OSA increases, the positive predictive values of both tests were decreased, while the negative predictive values were increased.
Conclusion
BACKGROUND:The aim of this study was to investigate the role of carbohydrate-rich drink (CHO) on perioperative discomfort, hemodynamic changes, and insulin response in patients undergoing surgery with spinal anesthesia.METHODS:Forty-four adult patients were assigned to one of the two groups of 22, namely preparation with CHO (CHO group) or fasting from midnight (control group). Ten different discomfort variables, blood glucose and insulin concentrations, and hemodynamic changes were recorded during the perioperative period.RESULTS:Preparation with CHO was effective in reducing hunger, thirst, malaise, unfitness, and, to some extent, anxiety (p < 0.05). Plasma glucose and insulin concentrations were increased in the CHO group (p < 0.05). Plasma glucose increased and insulin decreased in the control group (p < 0.05). In the control group, mean arterial pressure was lower compared to the CHO group (p < 0.05).CONCLUSIONS:Preparation with CHO before spinal anesthesia is advantageous due to reducing perioperative discomfort, improving insulin response and stabilizing mean arterial pressure.
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