Purpose: Pulmonary tuberculosis (PTB) is one of the major health problems in the elderly population, causing significant morbidity and mortality. The aim of this study is to evaluate the significance of the high-resolution computed tomography (HRCT) modality for the diagnosis of PTB, in comparison to culture test. Material and methods: Thoracic HRCT images of the study population, comprising 124 patients clinically suspected for PTB with smear and culture reports, were analysed for sensitivity and specificity of the HRCT test. Features of active PTB were centrilobular nodules, 'tree-in-bud' pattern densities, macro-nodules, consolidations, cavitary lesions, ground-glass opacities, and miliary nodules. Results: Among the study population, 108 cases presented HRCT features of active PTB and the remaining cases were negative but had presented a few features mimicking PTB. As inferred from positive culture test results, 106 cases had active PTB, the remaining cases were culture negative for PTB. False-positive (FP) or 'type I error' cases, and false-negative (FN) or 'type II error' cases were ascertained by Bayes' theorem. Sensitivity (true positive rate) and specificity (true negative rate) of HRCT test were 0.8125 and 0.8571, respectively. Conclusions: For proper diagnosis the predictive capability, as two values of 'a posteriori probability' , was computed; the mean value of 'a posteriori probability' for HRCT was 0.6358. When its culture test was positive, the HRCT test was 69.56-92.85% efficient in ascertaining positive results with a sample; on the other hand, when its culture test was negative it was 66.66-100% efficient for a negative result. Thus, the HRCT test is considerably dependable.
BACKGROUND: Coronavirus disease 2019(COVID-19) continues to spread all over world and is outpacing the resources and capacity of health care systems. This rapidly spreading COVID-19 infection is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been challenging the medical community and keeping the whole world in great threat to an unprecedented degree. OBJECTIVES: The objective of this review article is to describe details of social distancing, hand hygiene and wearing face masks including there role in controlling the current COVID-19 pandemic. METHOD: We conducted an electronic search of Google Scholar, Scopus, Medline and PubMed databases for articles between June to September 2021. RESULTS: The novel SARS-CoV-2 virus is transmitted from person to person by respiratory droplets or contact with an infected person. There are no established medications and vaccine available until now to restrain the transmission of the COVID-19 infection. Currently, social distancing, hand hygiene and wearing a mask are key steps to lower the transmission of the SARS-CoV-2 virus in COVID-19 pandemic. As this infection is highly contagious via a respiratory pathway through coughing, sneezing and contact with an infected surface, the spread can be reduced by the proper practice of social distancing, hand hygiene or frequent hand washing and wearing mask. These universal precautions should be done as COVID-19 patients may be asymptomatic. CONCLUSION: Social distancing, hand washing and wearing face masks are cheap and widely acceptable methods for the prevention of the COVID-19 infection. The goal of this review paper is to discuss social distancing, hand hygiene and face mask information, including its role in managing the current COVID-19 pandemic
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