The novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of the clinical syndrome COVID-19. Data on SARS-CoV-2 infection in pregnant women is rapidly accumulating and will help improve clinical guidelines for treatment. It is currently unknown if infection with human immunodeficiency virus (HIV) predisposes pregnant women to serious illness from SARS-CoV-2 infection. The greatest risk factors for pre-disposing patients with HIV to de-novo virulent viral infections includes non-adherence to combined antiretroviral therapy (cART) (Center for Disease Control and Prevention, 2020). We present the clinical course, treatment and outcome of a pregnant patient co-infected with HIV and SARS-CoV-2. We document an uncomplicated, full term delivery and highlight the adherence of cART in favorable outcome of pregnancy with SARS-CoV-2 and HIV coinfection.