About 500 million people suffer from malaria leading to death in 2-3 million cases every year, of which about 1 million are children. Horstman et al., 1985, and Weber et al., 1991, demonstrated an acute renal failure as a well-described complication of Plasmodium falciparum malaria in nonimmune adults and a major contributor to their mortality. In children, renal failure, though not very common, has become a rising issue leading to death. This study aims at determining the incidence of renal complication in malaria cases reported in children of Odisha. 108 cases of malaria who were admitted to Department of Paediatrics, SCB Medical College and Hospital and Sardar Vallab Bhai Patel Post Graduate Institute of Paediatrics, Cuttack, Odisha, India during the period from July 2006 to November 2008 were included in the prospective study. Extensive investigations were carried out to check for renal involvement in these cases. 50.9% of cases showed some form of renal involvement, most of which were recorded in age group of 5–10 years. Overall, males had a higher incidence than females. 62.7% of total cases infected with P. falciparum showed renal involvement though mixed infections with both P. falciparum and P. vivax had 100% renal involvement.

Background: Changes in QT interval is one of the important electrocardiographic parameters which are reported in many clinical conditions not only in adults but also among the pediatric age group. Diseases with a high risk of sudden deaths in the pediatric age group have initiated the interests among the researchers to focus on electrocardiographic studies. Aims and Objectives: This pilot study was done to obtain the normal QT values for the various age groups and both the genders of pediatric subjects. Materials and Methods: A cross-sectional study was conducted which included 162 healthy children (93 males and 69 females) and electrocardiographic recordings were taken. Subjects with congenital or acquired cardiovascular diseases were excluded from the study. Results: All the participants were divided into three age groups of 1-5 years, 6-10 years, and 11-15 years. It was found that heart rate was inversely proportional to QT/QTc interval while RR interval was directly proportional to both QT and QTc interval. With age, heart rate decreases but other electrocardiograms parameters increase progressively. Although the heart rate is inversely correlated with QT/QTc interval, there is positive correlation of QT/QTc with RR interval. Conclusion: Electrocardiography should be started as a routine investigation in pediatric subjects for the diagnosis of congenital and acquired cardiac diseases and arrhythmias which can be evident from QT interval determination.

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The present study is to correlate bleeding time and clotting time with blood pressure, pulse rate and respiratory rate. A total of 30 apparently healthy, male and female students aged 18-25 years, were included in the study. Bleeding time, clotting time, blood pressure, pulse rate, respiratory rate was recorded by standard methods. Significant positive correlation was present between DBP and Pulse rate with bleeding time (P<0.05). Significant negative correlation was observed between respiratory rate with bleeding time (P<0.05). Significant negative correlation was present between clotting time and systolic and diastolic blood pressure (P<0.05). Significant positive correlation was observed between pulse rate and respiratory rate with clotting time (P<0.01). Our study observes correlations between bleeding time and clotting time and blood pressure, pulse rate and respiratory rate. We recommend further detailed studies in this area to understand in detail about the associations, to support diagnostic importance of bleeding time and clotting time.