Background: Non alcoholic fatty liver disease (NAFLD) is abnormalities of metabolism resulting in fat deposition in the hepatocyte occurred in people who do not consume alcohol. Carbohydrate and fat intake, also visceral fat deposition has been studied as a risk factor of NAFLD, however the results remain elusive.Objective: To identity the nutritional and clinical risk factors of the incidence and severity of NAFLD.Methods: This study was done from June to December 2014 in the Dr. Kariadi Hospital Semarang. A case-control group was established comprising 33 patients with NAFLD based on the ultrasonography (USG) criteria (case group) and 34 healthy subject (control group). Carbohydrate and fat intake was assessed by using the food frequency questionnaire (FFQ), visceral fat deposition was measured by body impedance analysis (BIA), and clinical markers were obtained from laboratory data.Results: Carbohydrate intake, fat intake, and visceral fat deposition were risk factors of the incidence and severity of NAFLD (OR=7.8, CI95% 2.43-25.45; OR=5.9, CI95% 2.0-17.57; OR=50.7, CI95% 6.16-418.09) and (OR=0.9, CI95% 1.06-90.58; OR=14.6, CI95% 1.37-156.88; OR=6.6, CI95% 1.17-37.78). Multivariate regression showed that the most important risk factor of NAFLD for the incidence and severity were hypertriglyceridemia (OR=8.7, CI95% 2.20-34.44) and fat intake (OR=48.4, CI95% 2.78-844.1), respectively.Conclusion: High carbohydrate intake, fat intake, and high visceral fat deposition are risk factors of the incidence and severity of NAFLD. Hypertriglyceridemia and fat intake are the most important risk factor of NAFLD incidence and severity, respectively.

Penderita lepra selain ditemukan di rumah juga ada yang ditemukan di panti asuhan. Kondisi tempat tinggal yang berbeda tersebut memungkinkan perbedaan lingkungan, asupan gizi dan imunitas yang pada akhirnya mempengaruhi penularan kuman M. leprae. Tujuan penelitian ini adalah mengetahui perbedaan kadar IgM anti PGL-1 dan asupan gizi penderita lepra stadium subklinis yang tinggal di rumah bersama keluarga dengan penderita lepra stadium sublinis yang tinggal di panti asuhan. Studi observasional dengan pendekatan potong lintang ini dilakukan di Semarang, Jawa Tengah, Indonesia. Tigapuluh satu penderita lepra subklinis yang tinggal di panti asuhan dan 30 penderita lepra subklinis yang tinggal di rumah ikut dalam penelitian ini. Semua sampel diambil darah venanya, diperiksa kadar IgM anti PGL-1 nya dan dianalisis masukan nutriennya.Uji beda antara kedua kelompok dilakukan dengan independent t-test atau Mann Whitney test bila distribusi tidak normal. Terdapat perbedaan bermakna kadar IgM anti PGL-1, asupan protein, seng dan vitamin C (P < 0,05) antara kelompok yang tinggal di rumah dan panti asuhan.

No abstract

Cancer is a non-communicable disease whose prevalence is increasing every year. Comprehensive therapy must be carried out to handle it, one of the things that patients often forget is adherence to taking medication. Even the adherence rate of cancer patients to take medication, in an oncology center at a hospital in Semarang is quite low. If the patient is not regular in taking medication, it will make the disease more progressive and result in an even greater burden on the health budget. This must find a solution to solve it. One of them is by making a medication reminder application using technology that can be installed on the patient's smartphone. Objective to find out the relationship between giving a reminder application to adherence to taking medication in cancer patients. The study uses quantitative research with a Quasi Experiment Control Group Design, and a pre-test and post-test group design with a control group without randomization. The application of cancer telenutrition in the form of diet reminders has a positive relationship in increasing the weight of cancer patients (p<0.001) with a strong relationship of 0.711 (R squared >0.67). The use of reminder applications is associated with increasing adherence to taking medication in cancer patients. It is hoped that this research can be used as a basis for implementing information technology innovations in improving cancer service management practices in hospitals. Keywords: Cancer, Reminder Application, Medication Adherence  ABSTRAK Kanker adalah penyakit tidak menular yang saat ini prevalensinya meningkat setiap tahunnya. Terapi komperhensif harus dilakukan untuk menanganinya, salah satu hal yang sering dilupakan pasien adalah kepatuhan minum obat. Bahkan angka kepatuhan pasien kanker untuk meminum obat, di salah satu pusat onkologi di Rumah Sakit di Semarang cukup rendah. Dengan tidak teraturnya pasien dalam minum obat, akan membuat panyakit bertambah progresif dan mengakibatkan beban anggaran kesehatan yang semakin besar.  Hal ini harus dicarikan suatu solusi untuk memecahkannya. Salah satunya dengan membuat aplikasi pengingat minum obat dengan memanfaatkan teknologi yang dapat diinstal ke ponsel pintar pasien. Tujuan untuk mengetahui hubungan pemberian aplikasi pengingat terhadap kepatuhan minum obat pasien kanker. Studi menggunakan penelitian kuantitatif dengan Quasi Eksperiment Control Group Design,  dan rancangan pre test and post test group design dengan kelompok kontrol tanpa randomisasi. Aplikasi telenutrisi kanker dalam bentuk pengingat diit mempunyai hubungan positif dalam meningkatkan berat badan pasien kanker (p<0,001)  dengan hubungan kuat yakni 0,711(R squared >0.67). Penggunaan aplikasi pengingat berhubungan dengan peningkatan kepatuhan minum obat pasien kanker. Diharapkan penelitian ini dapat digunakan sebagai dasar penerapan inovasi teknologi informasi dalam meningkatkan praktek menajemen pelayanan kanker di Rumah Sakit. Kata Kunci: Kanker, Aplikasi Pengingat, Kepatuhan Minum Obat

<p align="center"><strong>ABSTRAK</strong></p><p><strong><em>Latar Belakang</em></strong><em>: Angka kejadian gizi buruk di Indonesia maupun di Provinsi Jawa Tengah dan Kota Semarang masih tinggi. Masalah tersebut disebabkan oleh kurangnya kesadaran dan pengetahuan terkait gizi di kalangan masyarakat, termasuk Aktivis Dasa Wisma. Salah satu alasan lainnya adalah kurangnya promotor gizi di tengah masyarakat, tokoh yang seharusnya berkaitan erat dengan kelompok sasaran, yaitu balita gizi buruk (stunting). Tujuan penelitian ini adalah melatih promotor gizi yang dapat melakukan deteksi dini dan pencegahan gizi buruk dengan baik dan efisien di tingkat Dasa Wisma sebagai upaya pencegahan stunting di tingkat masyarakat.</em><em></em></p><p><strong><em>Metode</em></strong><em>: Studi intervensi dengan rancangan kohort time series prospektif pada dua kelompok digunakan dalam penelitian ini. Tahapan kegiatannya adalah persiapan lapangan berupa Training of Trainer (TOT) bagi petugas gizi dan aktivis Dasa Wisma (66 aktivis terpilih), pengadaan sarana antropometrik penentuan status gizi, media, dan pelatihan bagi enumerator.</em></p><p><strong><em>Hasil</em></strong><em>: Aktivis Dasa Wisma yang dilatih mengalami peningkatan pengetahuan terkait gizi dan malnutrisi sebesar 2,66 poin (p&lt;0,05) dan peningkatan keterampilan terkait pengukuran status gizi sebesar 0,68 poin (p&lt;0,05).</em></p><p><strong><em>Kesimpulan</em></strong><em>: Peran Aktivis Dasa Wisma sangat penting untuk membantu ibu balita dalam melakukan pemantauan gizi anaknya; Selanjutnya, diharapkan semua ibu balita menyadari dan mempraktekkan keterampilan yang telah diperoleh untuk mencegah kejadian stunting sejak dini.</em></p><p> </p><p><strong>KATA KUNCI: </strong><em>malnutrisi; stunting; pelatihan; Dasa Wisma; Promotor Kesehatan</em></p><p align="center"><strong>ABSTRACT</strong></p><p><strong><em>Background</em></strong><em>: The incidence of malnutrition in Indonesia especially in Central Java Province and in Semarang City is still high. The problem was due to lack of awareness and knowledge related to nutrition in the community, including Housewives Peer Group Activists. Another reason is due to the absence of nutrition promotors, persons who are closely related to the target group, under five children who were stunted. The objective of this study was to train efficient promotors in doing early detection and prevention of malnutrition at Housewives Peer Group Activists level as an effort to prevent stunting at the community level. </em></p><p><strong><em>Methods:</em></strong><em> An intervention study with a case control design in two groups used in this study. The stages of the activities were field preparation in the form of training of trainers (TOT) for nutrition officers and Housewives Peer Group Activists (66 activists selected), procurement of anthropometric infrastructure for determining nutritional status, media, and training for enumerator. </em></p><p><strong><em>Result</em></strong><em>s: Housewives Peer Group Activists being trained had an increase in knowledge by 2.66 points (p &lt;0.05) and an increase in skills related to measuring nutritional status by 0.68 points (p &lt;0.05). </em></p><p><strong><em>Conclusion</em></strong><em>: The role of Housewives Peer Group Activists is very important in assisting mothers of children under five in conducting monitoring of their children’s nutrition; furthermore, it is hoped that all mothers of children under five realize and practice the skills they have acquired to prevent stunting</em><em>. </em></p><p><em> </em></p><p><strong>KEYWORD</strong><em>: malnutrition; stunting; training; housewives peer group activist; health promotor</em></p>