Oral fibrosarcoma (FSA) is a common oral tumour in dogs, and historically reported survival times after surgical excision range from 7.0 to 12.2 months with local recurrence rates of 32-57%. The purpose of this retrospective study was to report outcome in a cohort of dogs with oral FSA treated with surgical excision with or without adjuvant radiation therapy. Twenty-nine dogs with a histological diagnosis of FSA arising from the oral cavity that underwent surgical resection of their oral FSA were included in this study. Twenty-one dogs were treated with surgical excision alone and eight dogs with both surgery and radiation therapy. The median progression-free interval was >653 days. The median survival time was 743 days. The 1- and 2-year survival rates were 87.7 and 57.8%, respectively. Seven (24.1%) dogs developed local recurrence. Seven dogs (24.1%) developed metastasis.
Objectives
Patients with human immunodeficiency virus (HIV) vaccinated early in the flu season are more likely to get influenza or influenza like illness (ILL) compared to late vaccination.
Design
It is known that antibody titers wane over time, particularly among individuals with HIV infection. It is unclear if the timing of influenza vaccination within the flu season affects the probability of an influenza infection later during flu season.
Methods
A retrospective cohort study of HIV patients in care at Department of Veteran’s Affairs San Diego Healthcare System was conducted from 9/1/2005 – 5/31/2013. Among these patients, we evaluated if there was a relationship between the timing of influenza vaccination and incidence of laboratory confirmed influenza, influenza diagnosed by a physician, or influenza like illness (ILI).
Results
Patients who received influenza vaccine early in the season were more likely to contract influenza or ILI than patients who were vaccinated late (p<0.01). Vaccinated patients who developed influenza or ILI were more likely to do so later in the season (p<0.01).
Conclusion
HIV patients vaccinated early in the flu season were more likely to get influenza or ILI than those vaccinated later in the season.
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