IntroductionIt is widely believed that addiction entails a loss of free will, even though this point is controversial among scholars. There is arguably a downside to this belief, in that addicts who believe they lack the free will to quit an addiction might therefore fail to quit an addiction.MethodsA correlational study tested the relationship between belief in free will and addiction. Follow-up studies tested steps of a potential mechanism: 1) people think drugs undermine free will 2) people believe addiction undermines free will more when doing so serves the self 3) disbelief in free will leads people to perceive various temptations as more addictive.ResultsPeople with lower belief in free will were more likely to have a history of addiction to alcohol and other drugs, and also less likely to have successfully quit alcohol. People believe that drugs undermine free will, and they use this belief to self-servingly attribute less free will to their bad actions than to good ones. Low belief in free will also increases perceptions that things are addictive.ConclusionsAddiction is widely seen as loss of free will. The belief can be used in self-serving ways that may undermine people's efforts to quit.

No abstract

Magnetoencephalography (MEG) signals are influenced by skull defects. However, there is a lack of evidence of this influence during source reconstruction. Our objectives are to characterize errors in source reconstruction from MEG signals due to ignoring skull defects and to assess the ability of an exact finite element head model to eliminate such errors. A detailed finite element model of the head of a rabbit used in a physical experiment was constructed from magnetic resonance and co-registered computer tomography imaging that differentiated nine tissue types. Sources of the MEG measurements above intact skull and above skull defects respectively were reconstructed using a finite element model with the intact skull and one incorporating the skull defects. The forward simulation of the MEG signals reproduced the experimentally observed characteristic magnitude and topography changes due to skull defects. Sources reconstructed from measured MEG signals above intact skull matched the known physical locations and orientations. Ignoring skull defects in the head model during reconstruction displaced sources under a skull defect away from that defect. Sources next to a defect were reoriented. When skull defects, with their physical conductivity, were incorporated in the head model, the location and orientation errors were mostly eliminated. The conductivity of the skull defect material non-uniformly modulated the influence on MEG signals. We propose concrete guidelines for taking into account conducting skull defects during MEG coil placement and modeling. Exact finite element head models can improve localization of brain function, specifically after surgery.

This paper addresses the question of optimal sensor placement for magnetocardiographic field imaging. New magnetic sensor technologies allow less restrictive sensor positioning in this application. We develop a constraint framework for sensor positioning and use tabu search (TS) and particle swarm optimization (PSO) for finding an optimal set of sensors, whereby a new PSO algorithm is designed to fit the needs of our constraint framework. Numerical simulations are carried out with a three compartment boundary element torso model and a multi-dipole heart model. We find an optimal value of about 20 to 30 vectorial sensors and both TS and PSO yield similar sensor distributions. The comparison to sensors on regular grids shows that optimization of vectorial magnetic sensor setups may significantly improve reconstruction quality and that the number of sensors can be reduced