Structural damage is evident both in the peripapillary and in macular areas. Vascular damage seems to be less prominent, as it was seen only for the glaucoma group and at the radial peripapillary plexus. Diagnostic abilities are excellent for structural variables, less so but still good for peripapillary VD, and poor for macular VD.

The relatively fast translation of optical coherence tomography (OCT) from an optical measurement technology to a standard of care in ophthalmology was driven by its ability to address clear unmet diagnostic needs. OCT's further technological developments have expanded its clinical use by extending the imaging range (wider, deeper) and the imaging contrast (from morphology to blood flow). The translation of technical advances into clinical value is an ongoing process involving both the potential substitution of established diagnostics (such as fundus angiography) and the identification of novel feature‐disease correlations. This review looks into the development, the status and the prospects of OCT with regard to translation to clinical routine in ophthalmology.

The EZ disruption pattern could be an indicator for GA pattern progression, but is not a good quantitative tool to predict the size of GA in the overall population over a 1-year period except for patients without reticular pseudodrusen. The results in this specific population must be confirmed by further studies.

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